Metal-Functional Nucleic Acid Nanocomposite Based Biosensor
Metal-based nanomaterials are most commonly used carrier for construction of functional nucleic acids sensors. Including gold nanoparticles (AuNPs) and magnetic beads (MBs), they play important roles in signal transmission and amplification. Further, the combination between different functional nucleic acids and metal-based nanomaterials also give these sensors multiple detection ability and high sensitivity. In this chapter, the metal-nucleic acids nanocomposite sensors are classified according to the dimensional of functional nucleic acids and elaborated respectively.
KeywordsFunctional nucleic acids Metal-based nanomaterials Gold nanoparticles (AuNPs) Magnetic beads (MBs)
- 5.Y. Pang, Z. Rong, R. Xiao, S. Wang, “Turn on” and label-free core−shell Ag@ SiO2 nanoparticles-based metal-enhanced fluorescent (MEF) aptasensor for Hg2+. Sci. Rep. 5, 9451 (2015)Google Scholar
- 9.C.H. Chung, J.H. Kim, J. Jung, B.H. Chung, Nuclease-resistant DNA aptamer on gold nanoparticles for the simultaneous detection of Pb2+ and Hg2+ in human serum. Biosens. Bioelectron. 41, 827–832 (2013)Google Scholar