To Measure Lipid Profile in Serum Sample
Lipids are organic substances relatively insoluble in water but soluble in organic solvents and which are related to fatty acids. They are conc. storage form of energy as well as structural components of biological membranes. The main lipids present in plasma are cholesterol, triglycerides, phospholipids, and non-esterified fatty acids. Lipids are transported in plasma and other body compartments in the form of lipoproteins. The protein part of lipoprotein is called as apolipoproteins. The apolipoprotein plays an important role in lipid transport by activating or inhibiting enzymes involved in lipid metabolism and recognizing cell membrane surface receptors. The major lipoproteins are chylomicrons, very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and high-density lipoprotein (HDL). A lipid profile typically includes the estimation of total cholesterol, HDL, LDL, VLDL, and triglycerides.