To Determine the Uric Acid Concentration in Serum and Urine
Uric acid is the end product of purine metabolism (adenine and guanine) present in RNA and DNA. Uric acid is 2,6,8-trihydroxypurine and exists in keto and enol forms. It exists only as the monosodium and disodium salt. In plasma, uric acid is present as monosodium salt. The pool of uric acid in the body is about 1200 mg, out of which about half amount undergoes turnover daily, that is, about 600 mg/dl is formed daily and about the same amount is lost, of which about 75% is exerted through urine and about 25% destroyed by bacteria in the colon.