Indirubin comes from Indigofera tinctoria L., Baphicacanthus cusia Brem., Isatis tinctoria L., and Couroupita guianensis Aubl. The indirubin has been artificially synthesized. Indirubin has the effects of anti-inflammatory, antibacterial, detoxification, enhancing immune function, and has anticancer. Indirubin is used for the therapy of chronic myelocytic leukemia in clinical. It has the advantages of reliable clinical curative effect, small side effects, and no significant inhibitory effect on the bone marrow. Indirubin is an effective ingredient of medicine. Therefore, indirubin and its derivatives will become a new direction of research in the field of anticancer drugs.
KeywordsIndirubin Chronic myeloid leukemia Cancer
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