• Li Li
  • Li Zhang
  • Guan-Hua Du


Baicalin, a flavone glycoside, is the glucuronide of baicalein. As one of the effective components from radix scutellariae, baicalin has a variety of pharmacological activities such as antiviral, antivirus, removal of oxygen free radicals, antioxidant, antipyretic, analgesic, anti-inflammatory, antitumor, cardiovascular protecting, cerebrovascular and neuron protecting, liver protecting, and prevention or treatment of diabetes and its complications. It can be used alone or in combination with other drugs for the treatment of the disease such as acute and chronic hepatitis and persistent hepatitis. However, due to the low bioavailability of baicalin, a large number of studies have shown that baicalein is the ingredient with more prominent activities compared with baicalin. Therefore, it is a potent valuable drug and deserves further research and development.


Baicalin Baicalein Radix scutellariae Hepatitis 


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© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2018

Authors and Affiliations

  1. 1.Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical ScreeningInstitute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

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