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Daphnetin

  • Lan Sun
  • Rui Zhao
  • Xiu-Ying Yang
  • Guan-Hua DuEmail author
Chapter

Abstract

Daphnetin is mainly extracted from Yu Ruixiang Changbai Daphne. Daphnetin has the pharmacological effects on cardiovascular system, central nervous system, and immune system, which made it mainly used for treatment of coronary heart disease, occlusive vascular disease, and Buerger’s disease in clinical. In the 1970s, the artificial synthesis of daphnetin, which promoted R&D, makes it a landmark of new drug discovery in China. Daphnetin has extensive pharmacological effects, but pharmacological researches are still based on animal experiments. Pharmacodynamics, pharmacokinetics, and clinical research for other indications are needed as soon as possible.

Keywords

Daphnetin Changbai daphne Coronary heart disease 

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Copyright information

© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2018

Authors and Affiliations

  1. 1.Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

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