Tetrandrine (Tet) is a dibenzyl isoquinoline alkaloid, which is extracted from the root of Stephania tetrandra S. Moore (Fěn Fánɡ Jǐ) of Menispermaceae. Tetrandrine has strong biological effects on the cardiovascular diseases, fibrosis, tumors, portal vein and pulmonary hypertension, liver diseases, and immunological diseases. Current researches showed that tetrandrine is superior to conventional therapies in clinical treatment of silicosis. Other pharmacological effects of tetrandrine are still under research. As a traditional Chinese calcium antagonist, tetrandrine has significant effects on cardiovascular and inflammatory diseases with relatively fewer side effects, which grants it great potential for further explorations and clinical applications.
KeywordsTetrandrine Alkaloid Cardiovascular diseases Clinical applications
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