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Puerarin

  • Yue-Rong Zhao
  • Li-Da Du
  • Li Zhang
  • Guan-Hua Du
Chapter

Abstract

Puerarin is an isoflavone component extracted from Pueraria lobata (Willd.) Ohwi and has widely protecting functions on the cardiovascular system, nervous system, glucose and lipid metabolism, osteoporosis, liver injury and inflammation. Puerarin has a great value of utilization due to its less adverse reactions and wide security range. The most widely used medicinal formulations of puerarin in the clinical area are puerarin injection. However, puerarin is difficult to absorb orally. In the long run, modifying the structure of puerarin and developing new types of dosage forms to improve bioavailability and selectivity will be effective to enhance its pharmacological activities, so as to expand the clinical application of puerarin and its derivatives.

Keywords

Puerarin Isoflavone Pharmacological effects 

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Copyright information

© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2018

Authors and Affiliations

  • Yue-Rong Zhao
    • 1
  • Li-Da Du
    • 2
  • Li Zhang
    • 1
  • Guan-Hua Du
    • 1
  1. 1.Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina
  2. 2.School of Biomedical SciencesChinese University of Hong KongHong KongChina

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