Advertisement

Curcumin

  • Tian-yi Yuan
  • Guan-Hua DuEmail author
Chapter

Abstract

Curcumin is the principal curcuminoid of turmeric (Curcuma longa). It is sold as an herbal supplement, cosmetic ingredient, food flavoring, and food coloring. In China, curcumin is mainly used in food, while in Western countries, it has been regarded as a health-care product. Curcumin has been proved to have multiple pharmacological effects including anti-fibrosis, antitumor, anticancer effects, and so on. As its broad biological activities, it is applied in a lot of diseases such as hyperlipidemia, infection, and cancer. However, curcumin still needs research to confirm its effects and mechanisms and find its exact indications. There is still a long way to go to make curcumin better applied in clinical practice in the future.

Keywords

Curcumin Food additives Wide application 

References

  1. 1.
    Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013;15(1):195–218.CrossRefGoogle Scholar
  2. 2.
    Gupta SC, Kismali G, Aggarwal BB. Curcumin, a component of turmeric: from farm to pharmacy. Biofactors. 2013;39(1):2–13.CrossRefGoogle Scholar
  3. 3.
    Prasad S, Gupta SC, Tyagi AK, Aggarwal BB. Curcumin, a component of golden spice: from bedside to bench and back. Biotechnol Adv. 2014;32(6):1053–64.CrossRefGoogle Scholar
  4. 4.
    Schraufstatter E, Bernt H. Antibacterial action of curcumin and related compounds. Nature. 1949;164(4167):456.CrossRefGoogle Scholar
  5. 5.
    Wu HC, Zhang B. The mechanism progress of anti-fibrosis by curcumin. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013;33(1):135–7.PubMedGoogle Scholar
  6. 6.
    Vallianou NG, Evangelopoulos A, Schizas N, Kazazis C. Potential anticancer properties and mechanisms of action of curcumin. Anticancer Res. 2015;35(2):645–51.PubMedGoogle Scholar
  7. 7.
    He Y, Yue Y, Zheng X, Zhang K, Chen S, Du Z. Curcumin, inflammation, and chronic diseases: how are they linked? Molecules. 2015;20(5):9183–213.CrossRefGoogle Scholar
  8. 8.
    Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A review on antibacterial, antiviral, and antifungal activity of curcumin. Biomed Res Int. 2014;2014:186864.PubMedGoogle Scholar
  9. 9.
    Sahebkar A. A systematic review and meta-analysis of randomized controlled trials investigating the effects of curcumin on blood lipid levels. Clin Nutr. 2014;33(3):406–14. eng.CrossRefGoogle Scholar
  10. 10.
    Wang Q, Wang K. Metabolism of curcumin. Chin Pharmacol Bull. 2003;10:1097–101.Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2018

Authors and Affiliations

  1. 1.Beijing Key Laboratory of Drug Targets Identification and Drug ScreeningCentre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Personalised recommendations