Arbutin is extracted from the bearberry plant or other plants. Arbutin could effectively inhibit the activity of tyrosinase in skin cells and block the formation of melanin. Arbutin is therefore used as a skin-lightening agent. In the history of arbutin R&D, it is found that arbutin is a hydroquinone compound with two epimers, α and β arbutin. Alpha arbutin is safer and has a stronger inhibitory effect on tyrosinase. Moreover, arbutin is a major component of medicine for treating burn and scald, characterized by rapid elimination of pain and swelling and fast healing, leaving no scars. Arbutin can also be used as raw materials for intestinal anti-inflammatory drug, with sterilization, anti-inflammatory effect, and nontoxic side effects.
Arbutin Whitening effects Cosmetics
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1.Liaoning Key Laboratory of Behavior and Cognitive Neuroscience, Department of PharmacologyShenyang Medical CollegeShenyangChina
2.School of Biomedical SciencesChinese University of Hong KongHong KongChina
3.Beijing Key Laboratory of Drug Targets Identification and Drug ScreeningCentre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina