Complications of Thoracoscopic-Laparoscopic Esophagectomy and the Treatment



The long operation time and complexity of esophageal cancer surgery and patient malnutrition all contribute to the higher incidence of postoperative complications.

Complications may happen during or after esophageal cancer surgery. Generally, the intraoperative complications include bleeding, RLN injury, and tracheobronchial laceration; the postoperative complications include pulmonary infection, esophagogastric anastomotic leak, anastomotic stenosis, etc. Esophagogastric anastomotic leak is one of the most commonly seen severe complications of the thoracoscopic-laparoscopic esophagectomy and a major cause of death after surgery.

The prevention and treatment of perioperative complications are particularly important for thoracoscopic esophagectomy as a new technique. Frequent occurrence of complications will undermine the confidence of doctors and the trust of patients and consequently restrict the development of this new technique.


Perioperative period Complication Bleeding Anastomotic leak Anastomotic stenosis 


  1. Ahmed S, Fontaine JP, Thomas NG. Pancreatic herniation after transhiatal esophagectomy. Ann Thorac Surg. 2010;89(1):308–9.PubMedCrossRefPubMedCentralGoogle Scholar
  2. Akutsu Y, Matsuhara H. Perioperative management for the prevention of postoperative pneumonia with esophageal surgery. Ann Thorac Cardiovasc Surg. 2009;15(5):280–5.PubMedPubMedCentralGoogle Scholar
  3. Aly A, Watson DI. Diaphragmatic hernia after minimally invasive esophagectomy. Dis Esophagus. 2004;17(2):183–6.PubMedCrossRefPubMedCentralGoogle Scholar
  4. Amar D, Roistacher N, Burt M, et al. Clinical and echocardiographic correlates of symptomatic tachydysrhythmias after noncardiac thoracic surgery. Chest. 1995;108(2):349–54.PubMedCrossRefPubMedCentralGoogle Scholar
  5. Amar D, Goenka A, Zhang H, et al. Leukocytosis and increased risk of atrial fibrillation after general thoracic surgery. Ann Thorac Surg. 2006;82(3):1057–61.PubMedCrossRefPubMedCentralGoogle Scholar
  6. Ammori JB, Pickens A, Chang AC, et al. Tension chylothorax. Ann Thorac Surg. 2006;82(2):729–30.PubMedCrossRefPubMedCentralGoogle Scholar
  7. Anile M, Francioni F, Diso D, et al. Esophageal stent displacement in left main bronchus. Ann Thorac Surg. 2007;84(5):1767.PubMedCrossRefPubMedCentralGoogle Scholar
  8. Avendano CE, Flume PA, Silvestri GA, et al. Pulmonary complications after esophagectomy. Ann Thorac Surg. 2002;73(3):922–6.PubMedCrossRefPubMedCentralGoogle Scholar
  9. Bakhos C, Alazemi S, Michaud G, et al. Staged repair of benign tracheo-neo-esophageal fistula 12 years after esophagectomy for esophageal cancer. Ann Thorac Surg. 2010;90(6):e83–5.PubMedCrossRefPubMedCentralGoogle Scholar
  10. Barbier PA, Becker CD, Wagner HE. Esophageal carcinoma: patient selection for transhiatal esophagectomy. A prospective analysis of 50 consecutive cases. World J Surg. 1988a;12(2):263–9.PubMedCrossRefPubMedCentralGoogle Scholar
  11. Barbier PA, Luder PJ, Schupfer C, et al. Quality of life and patterns of recurrence following transhiatal esophagectomy for cancer: results of a prospective follow-up in 50 patients. World J Surg. 1988b;12(2):270–6.PubMedCrossRefPubMedCentralGoogle Scholar
  12. Bayliff CD, Massel DR, Inculet RI, et al. Propranolol for the prevention of postoperative arrhythmias in general thoracic surgery. Ann Thorac Surg. 1999;67(1):182–6.PubMedCrossRefPubMedCentralGoogle Scholar
  13. Beck SM, Malay MB, Gagne DJ, et al. Experimental model of laparoscopic gastric ischemic preconditioning prior to transhiatal esophagectomy. Surg Endosc. 2011;25(8):2470–7.PubMedCrossRefPubMedCentralGoogle Scholar
  14. Ben-David K, Sarosi GA, Cendan JC, et al. Decreasing morbidity and mortality in 100 consecutive minimally invasive esophagectomies. Surg Endosc. 2012;26(1):162–7.PubMedCrossRefPubMedCentralGoogle Scholar
  15. Betti S, Sironi A, Saino G, et al. Effect of the informed consent process on anxiety and comprehension of patients undergoing esophageal and gastrointestinal surgery. J Gastrointest Surg. 2011;15(6):922–7.PubMedCrossRefPubMedCentralGoogle Scholar
  16. Bittar G, Friedman HS. The arrhythmogenicity of theophylline: a multivariate analysis of clinical determinants. Chest. 1991;99(6):1415–20.PubMedCrossRefPubMedCentralGoogle Scholar
  17. Blackmon SH, Santora R, Schwarz P, et al. Utility of removable esophageal covered self-expanding metal stents for leak and fistula management. Ann Thorac Surg. 2010;89(3):931–7.PubMedCrossRefPubMedCentralGoogle Scholar
  18. Boone J, Verhage RJ, van der Sluis PC, et al. Incarcerated hiatal hernia after robot-assisted esophagectomy: transhiatal versus thoracoscopic approach. Surg Endosc. 2012;26(3):886–7.PubMedCrossRefPubMedCentralGoogle Scholar
  19. Braghetto I, Csendes A, Cardemil G, et al. Open transthoracic or transhiatal esophagectomy versus minimally invasive esophagectomy in terms of morbidity, mortality and survival. Surg Endosc. 2006;20(11):1681–6.PubMedCrossRefPubMedCentralGoogle Scholar
  20. Burnett CM, Rosernurgy CM, Pfeiffer EA, et al. Life-threatening acute posterior mediastinitis due to esophageal perforation. Ann Thorac Surg. 1990;49(6):979–83.PubMedCrossRefPubMedCentralGoogle Scholar
  21. Burt M, Diehl W, Martini N, et al. Malignant esophagorespiratory fistula: management options and survival. Ann Thorac Surg. 1991;52(6):1222–9.PubMedCrossRefPubMedCentralGoogle Scholar
  22. Buunen M, Rooijens PP, Smaal HJ, et al. Vascular anatomy of the stomach related to gastric tube construction. Dis Esophagus. 2008;21(3):272–4.PubMedPubMedCentralCrossRefGoogle Scholar
  23. Cadiere GB, Torres R, Dapri G, et al. Thoracoscopic and laparoscopic oesophagectomy improves the quality of extended lymphadenectomy. Surg Endosc. 2006;20(8):1308–9.PubMedCrossRefPubMedCentralGoogle Scholar
  24. Cerfolio RJ, Talati A, Bryant AS. Changes in pulmonary function tests after neoadjuvant therapy predict postoperative complications. Ann Thorac Surg. 2009;88(3):930–6.PubMedCrossRefPubMedCentralGoogle Scholar
  25. Cheng W, Heitmiller RF, Jones B. Subacute ischemia of the colon esophageal interposition. Ann Thorac Surg. 1994;57(4):899–903.PubMedCrossRefPubMedCentralGoogle Scholar
  26. Chernow B, Alexander HR, Smallridge RC, et al. Hormonal responses to graded surgical stress. Arch Intern Med. 1987;147(7):1273–8.PubMedCrossRefPubMedCentralGoogle Scholar
  27. Cho KR, Jo WM. Superior mesenteric artery syndrome after esophagectomy with cervical esophagogastrostomy. Ann Thorac Surg. 2006;82(5):e37–8.PubMedCrossRefPubMedCentralGoogle Scholar
  28. Cho S, Kim JW, Lee H, et al. Intramural hematoma of gastric tube after Ivor Lewis operation. Ann Thorac Surg. 2010;89(6):2016–7.PubMedCrossRefPubMedCentralGoogle Scholar
  29. Cole WR, Petit R, Bernard HR. Factors affecting incidence of anastomotic leak following esophagogastrectomy: an analysis. Ann Thorac Surg. 1968;6(4):396–400.PubMedCrossRefPubMedCentralGoogle Scholar
  30. Craig SR, Adam DJ, Yap PL, et al. Effect of blood transfusion on survival after esophagogastrectomy for carcinoma. Ann Thorac Surg. 1998;66(2):356–61.PubMedCrossRefPubMedCentralGoogle Scholar
  31. Cui Y. Pulmonary complication after esophagectomy results from multiple factors. Ann Thorac Surg. 2002;74(5):1747.PubMedCrossRefPubMedCentralGoogle Scholar
  32. D’Journo XB, Martin J, Gaboury L, et al. Roux-en-Y diversion for intractable reflux after esophagectomy. Ann Thorac Surg. 2008;86(5):1646–52.PubMedCrossRefPubMedCentralGoogle Scholar
  33. Daiko H, Nishimura M, Hayashi R, et al. Diaphragmatic herniation after esophagectomy for carcinoma of the esophagus: a report of two cases. Japan Esophageal Society and Springer. 2010;7:169–172.CrossRefGoogle Scholar
  34. Denk PM, Gatta P, Swanstrm LL. Prone thoracoscopic thoracic duct ligation for postsurgical chylothorax. Surg Endosc. 2008;22(12):2742.PubMedCrossRefPubMedCentralGoogle Scholar
  35. Diana M, Hubner M, Vuilleumier H, et al. Redistribution of gastric blood flow by embolization of gastric arteries before esophagectomy. Ann Thorac Surg. 2011;91(5):1546–51.PubMedCrossRefPubMedCentralGoogle Scholar
  36. Dimick JB, Goodney PP, Orringer MB, et al. Specialty training and mortality after esophageal cancer resection. Ann Thorac Surg. 2005;80(1):282–6.PubMedCrossRefPubMedCentralGoogle Scholar
  37. Duranceau A, Jamieson GG. Malignant tracheoesophageal fistula. Ann Thorac Surg. 1984;37(4):346–54.PubMedCrossRefPubMedCentralGoogle Scholar
  38. Easterling CS, Bousamra M II, Lang IM, et al. Pharyngeal dysphagia in postesophagectomy patients: correlation with deglutitive biomechanics. Ann Thorac Surg. 2000;69(4):989–92.PubMedCrossRefPubMedCentralGoogle Scholar
  39. Engelman E, Maeyens C. Effect of preoperative single-dose corticosteroid administration on postoperative morbidity following esophagectomy. J Gastrointest Surg. 2010;14(5):788–804.PubMedCrossRefPubMedCentralGoogle Scholar
  40. Falk RH, Leavitt JJ. Digoxin for atrial fibrillation: a drug whose time has gone. Ann Intern Med. 1991;114(7):573–5.PubMedCrossRefPubMedCentralGoogle Scholar
  41. Ferguson MK, Celauro AD, Prachand V. Prediction of major pulmonary complications after esophagectomy. Ann Thorac Surg. 2011;91(5):1494–501.PubMedCrossRefPubMedCentralGoogle Scholar
  42. Ferraris VA, Davenport DL, Saha SP, et al. Intraoperative transfusion of small amounts of blood heralds worse postoperative outcome in patients having noncardiac thoracic operations. Ann Thorac Surg. 2011;91(6):1674–80.PubMedCrossRefPubMedCentralGoogle Scholar
  43. Fok M, Law SY, Wong J. Neodymium: yttrium-aluminum-garnet laser for the treatment of tracheobronchial recurrences in esophageal carcinomas. Ann Thorac Surg. 1994;58(5):1415–8.PubMedCrossRefPubMedCentralGoogle Scholar
  44. Forshaw MJ, Strauss DC, Davies AR, et al. Is cardiopulmonary exercise testing a useful test before esophagectomy. Ann Thorac Surg. 2008;85(1):294–9.PubMedCrossRefPubMedCentralGoogle Scholar
  45. Freeman RK, Wait MA. Port site metastasis after laparoscopic staging of esophageal carcinoma. Ann Thorac Surg. 2001;71(3):1032–4.PubMedCrossRefPubMedCentralGoogle Scholar
  46. Fry WA, Siddiqui A, Pensler JM, et al. Thoracoscopic implantation of cancer with a fatal outcome. Ann Thorac Surg. 1995;59(1):42–5.PubMedCrossRefPubMedCentralGoogle Scholar
  47. Garcia A, Flores RM, Schattner M, et al. Endoscopic retrograde dilation of completely occlusive esophageal strictures. Ann Thorac Surg. 2006;82(4):1240–3.PubMedCrossRefPubMedCentralGoogle Scholar
  48. Gillis RA, Quest JA. The role of the nervous system in the cardiovascular effects of digitalis. Pharmacol Rev. 1979;31(1):19–97.PubMedPubMedCentralGoogle Scholar
  49. Gomes MN, Kroll S, Spear SL. Mediastinal tracheostomy. Ann Thorac Surg. 1987;43(5):539–43.PubMedCrossRefPubMedCentralGoogle Scholar
  50. Gorenstein LA, Abel JG, Patterson GA. Pericardial repair of a tracheal laceration during transhiatal esophagectomy. Ann Thorac Surg. 1992;5(4):784–6.CrossRefGoogle Scholar
  51. Green DA, Moskowitz WB, Shepherd RW. Closure of a broncho-to-neoesophageal fistula using an Amplatzer Septal Occluder device. Ann Thorac Surg. 2010;89(6):2010–2.PubMedCrossRefPubMedCentralGoogle Scholar
  52. Grillo HC, Mathisen DJ. Cervical exenteration. Ann Thorac Surg. 1990;49(3):401–8.PubMedCrossRefPubMedCentralGoogle Scholar
  53. Grotenhuis BA, van Hagen P, Reitsma JB, et al. Validation of a nomogram predicting complications after esophagectomy for cancer. Ann Thorac Surg. 2010;90(3):920–5.PubMedCrossRefPubMedCentralGoogle Scholar
  54. Guo W, Zhao YP, Jiang YG, et al. Prevention of postoperative chylothorax with thoracic duct ligation during video-assisted thoracoscopic esophagectomy for cancer. Surg Endosc. 2012;26(5):1332–6.PubMedCrossRefPubMedCentralGoogle Scholar
  55. Hall A, Older P. Cardiopulmonary exercise testing accurately predicts risk of major surgery including esophageal resection: letter 1. Ann Thorac Surg. 2009;87(2):670–1.PubMedCrossRefPubMedCentralGoogle Scholar
  56. Hamai Y, Hihara J, Emi M, et al. Skin tube reconstruction for esophageal defect due to postoperative complication. Ann Thorac Surg. 2009;87(5):1605–7.PubMedCrossRefPubMedCentralGoogle Scholar
  57. Han XW, Li YD, Wu G, et al. New covered mushroom-shaped metallic stent for managing anastomotic leak after esophagogastrostomy with a wide gastric tube. Ann Thorac Surg. 2006;82(2):702–6.PubMedCrossRefPubMedCentralGoogle Scholar
  58. Hayashi K, Ando N, Ozawa S, et al. Gastric tube-to-tracheal fistula closed with a latissimus dorsi myocutaneous flap. Ann Thorac Surg. 1999;68(2):561–2.PubMedCrossRefPubMedCentralGoogle Scholar
  59. Hazelrigg SR, Nunchuck SK, LoCicero J. Video-assisted thoracic surgery group data. Ann Thorac Surg. 1993;56(5):1039–44.PubMedCrossRefPubMedCentralGoogle Scholar
  60. Heitmiller RF. Intrathoracic manifestation of cervical anastomotic leaks. Ann Thorac Surg. 2006;82(1):383.PubMedCrossRefPubMedCentralGoogle Scholar
  61. Hendren WG, Miller JI. Isolated, contained esophagobronchial fistula complicating esophagogastrectomy. Ann Thorac Surg. 1988;46(4):457–8.PubMedCrossRefPubMedCentralGoogle Scholar
  62. Hu J, Li R, Sun L. Influence of esophageal carcinoma operations on gastroesophageal reflux. Ann Thorac Surg. 2004;78(1):298–302.PubMedCrossRefPubMedCentralGoogle Scholar
  63. Javed A, Agarwal AK. Laparoscopic retrosternal bypass for corrosive stricture of the esophagus. Surg Endosc. 2012;26:3344–9.PubMedCrossRefPubMedCentralGoogle Scholar
  64. Josephson ME, Kastor JA. Supraventricular tachycardia: mechanisms and management. Ann Intern Med. 1977;87(3):346–58.PubMedCrossRefPubMedCentralGoogle Scholar
  65. Kaiser LR, Bavaria JE. Complications of thoracoscopy. Ann Thorac Surg. 1993;56(3):796–8.PubMedCrossRefPubMedCentralGoogle Scholar
  66. Kamath MV, Rubin JW ERG, et al. Esophageal mucocele: a complication of blind loop esophagus. Ann Thorac Surg. 1987;43(3):263–9.PubMedCrossRefPubMedCentralGoogle Scholar
  67. Katariya K, Harvey JC, Pina E, et al. Complications of transhiatal esophagectomy. J Surg Oncol. 1994;57(3):157–63.PubMedCrossRefPubMedCentralGoogle Scholar
  68. Kaufman J, Thongsuwan N, Stern E, et al. Esophageal-pericardial fistula with purulent pericarditis secondary to esophageal carcinoma presenting with tamponade. Ann Thorac Surg. 2003;75(1):288–9.PubMedCrossRefPubMedCentralGoogle Scholar
  69. Kayani B, Okabayashi K, Ashrafian H, et al. Does obesity affect outcomes in patients undergoing esophagectomy for cancer? A meta-analysis. World J Surg. 2012;36(8):1785–95.PubMedCrossRefPubMedCentralGoogle Scholar
  70. Kent MS, Pennathur A, Fabian T, et al. A pilot study of botulinum toxin injection for the of delayed of gastric emptying following esophagectomy. Surg Endosc. 2007;21(5):754–7.PubMedCrossRefPubMedCentralGoogle Scholar
  71. Kilic A, Schuchert MJ, Pennathur A, et al. Impact of obesity on perioperative outcomes of minimally invasive esophagectomy. Ann Thorac Surg. 2009;87(2):412–5.PubMedCrossRefPubMedCentralGoogle Scholar
  72. Kim WJ, Choi EJ, Oh YW, et al. Gastropericardial fistula-induced pyopneumopericardium after esophagectomy with esophagogastrectomy. Ann Thorac Surg. 2011;91(1):10–1.CrossRefGoogle Scholar
  73. Kinjo Y, Kurita N, Nakamura F, et al. Effectiveness of combined thoracoscopic-laparoscopic esophagectomy: comparison of postoperative complications and midterm oncological outcomes in patients with esophageal cancer. Surg Endosc. 2012;26(2):381–90.PubMedCrossRefPubMedCentralGoogle Scholar
  74. Kinugasa S, Tachibana M, Yoshimura H, et al. Esophageal resection in elderly esophageal carcinoma patients: improvement in postoperative complications. Ann Thorac Surg. 2001;71(2):414–8.PubMedCrossRefPubMedCentralGoogle Scholar
  75. Kobayashi M, Koh M, Irinoda T, et al. Stroke volume variation as a predictor of intravascular volume depression and possible hypotension during the early postoperative period after esophagectomy. Ann Surg Oncol. 2009;16(5):1371–7.PubMedCrossRefPubMedCentralGoogle Scholar
  76. Konno O, Tezuka T, Muto A, et al. Postoperative arrhythmia after operation for esophageal cancer. J Jpn Assoc Thorac Surg. 1993;41(1):45–51.Google Scholar
  77. Korst RJ, Port JL, Lee PC, et al. Intrathoracic manifestations of cervical anastomotic leaks after transthoracic esophagectomy for carcinoma. Ann Thorac Surg. 2005;80(4):1185–90.PubMedCrossRefPubMedCentralGoogle Scholar
  78. Kotzampassakis N, Christodoulou M, Krueger T, et al. Esophageal leaks repaired by a muscle onlay approach in the presence of mediastinal sepsis. Ann Thorac Surg. 2009;88(3):966–72.PubMedCrossRefPubMedCentralGoogle Scholar
  79. Kron IL, Johnson AM, Morgan RF. Gastrotracheal fistula: a late complication after transhiatal esophagectomy. Ann Thorac Surg. 1989;47(5):767–8.PubMedCrossRefPubMedCentralGoogle Scholar
  80. Krowka MJ, Pairolero PC, Trastek VF, et al. Cardiac dysrhythmias following pneumonectomy: clinical correlates and prognostic significance. Chest. 1987;91(4):490–5.PubMedCrossRefPubMedCentralGoogle Scholar
  81. Lagarde SM, Omloo JM, de Jong K, et al. Incidence and management of chyle leakage after esophagectomy. Ann Thorac Surg. 2005;80(2):449–54.PubMedCrossRefPubMedCentralGoogle Scholar
  82. Lagarde SM, Reitsma JB, Maris AK, et al. Preoperative prediction of the occurrence and severity of complications after esophagectomy for cancer with use of a nomogram. Ann Thorac Surg. 2008;85(6):1938–45.PubMedCrossRefPubMedCentralGoogle Scholar
  83. Lai FC, Chen L, Tu YR, et al. Prevention of chylothorax complicating extensive esophageal resection by mass ligation of thoracic duct: a random control study. Ann Thorac Surg. 2011;91(6):1770–4.PubMedCrossRefPubMedCentralGoogle Scholar
  84. Landreneau RJ, Hazelrigg SR, Mack MJ, et al. Postoperative pain-related morbidity: video assisted thoracic surgery versus thoracotomy. Ann Thorac Surg. 1993;56(6):1285–9.PubMedCrossRefPubMedCentralGoogle Scholar
  85. Langer FB, Wenzl E, Prager G, et al. Management of postoperative leaks with the polyflex self-expanding; covered plastic stent. Ann Thorac Surg. 2005;79(2):398–403.PubMedCrossRefPubMedCentralGoogle Scholar
  86. Lanuti M, de Delva PE, Maher A, et al. Feasibility and outcomes of an early extubation policy after esophagectomy. Ann Thorac Surg. 2006;82(6):2037–41.PubMedCrossRefPubMedCentralGoogle Scholar
  87. Lanuti M, DeDelva P, Morse CR, et al. Management of delayed gastric emptying after esophagectomy with endoscopic balloon dilatation of the pylorus. Ann Thorac Surg. 2011;91(4):1019–24.PubMedCrossRefPubMedCentralGoogle Scholar
  88. Law S. Esophagectomy without mortality: what can surgeons do. J Gastrointest Surg. 2010;14(Suppl 1):S101–7.PubMedCrossRefPubMedCentralGoogle Scholar
  89. Le Pimpec-Barthes F, D’Attellis N, Dujon A, et al. Chylothorax complicating pulmonary resection. Ann Thorac Surg. 2002;73(6):1714–9.PubMedCrossRefPubMedCentralGoogle Scholar
  90. Lee HS, Kim MS, Lee JM, et al. Intrathoracic gastric emptying of solid food after esophagectomy for esophageal cancer. Ann Thorac Surg. 2005a;80(2):443–7.PubMedCrossRefPubMedCentralGoogle Scholar
  91. Lee HS, Lee JM, Kim MS, et al. Low-dose steroid therapy at an early phase of postoperative acute respiratory distress syndrome. Ann Thorac Surg. 2005b;79(2):405–10.PubMedCrossRefPubMedCentralGoogle Scholar
  92. Lee JI, Choi S, Sung J. A flow visualization model of gastric emptying in the intrathoracic stomach after esophagectomy. Ann Thorac Surg. 2011;91(4):1039–45.PubMedCrossRefPubMedCentralGoogle Scholar
  93. Leobon B, Roux D, Mugniot A, et al. Endovascular treatment of thoracic aortic fistulas. Ann Thorac Surg. 2002;74(1):247–9.PubMedCrossRefPubMedCentralGoogle Scholar
  94. Levine EA. Radiation-induced secondary malignancy of the esophagus: reply. Ann Thorac Surg. 2001;72(2):669.CrossRefGoogle Scholar
  95. Liu HP, Chang GH, Lin PJ, et al. Thoracoscopic-assisted lobectomy: preliminary experience and results. Chest. 1995a;107(3):853–5.PubMedCrossRefPubMedCentralGoogle Scholar
  96. Liu HP, Lin PJ, Hsieh MJ, et al. Application of thoracoscopy for lung metastases. Chest. 1995b;107(1):266–8.PubMedCrossRefPubMedCentralGoogle Scholar
  97. Lolley DM, Ray JF, Ransdell HT, et al. Management of malignant esophagorespiratory fistula. Ann Thorac Surg. 1978;25(6):516–20.PubMedCrossRefPubMedCentralGoogle Scholar
  98. Low DE, Kunz S, Schembre D, et al. Esophagectomy-It’s not just about mortality anymore: standardized perioperative clinical pathways improve outcomes in patients with esophageal cancer. J Gastrointest Surg. 2007;11(11):1395–402.PubMedCrossRefPubMedCentralGoogle Scholar
  99. Low DE, Kuppusamy M, Hashimoto Y, et al. Comparing complications of esophagectomy and pancreaticoduodenectomy and potential impact on hospital systems utilizing the accordion severity grading system. J Gastrointest Surg. 2010;14(11):1646–52.PubMedCrossRefPubMedCentralGoogle Scholar
  100. Lowe C, Subar D, Hall C, et al. Hiatal hernias presenting as a late complication of laparoscopic-assisted cardio-oesophagectomy. Hernia. 2010;14(2):211–3.PubMedCrossRefPubMedCentralGoogle Scholar
  101. Mannell A, McKnight A, Esser JD. Role of pyloroplasty in the retrosternal stomach: results of a prosepective, randomized, controlled trial. Br J Surg. 1990;77(1):57–9.PubMedCrossRefPubMedCentralGoogle Scholar
  102. Marcon F, Irani K, Aquino T, et al. Percutaneous treatment of thoracic duct injuries. Surg Endosc. 2011;25(9):2844–8.PubMedCrossRefPubMedCentralGoogle Scholar
  103. Mariette C, Taillier G, Seuningen IV, et al. Factors affecting postoperative course and survival after En bloc resection for esophageal carcinoma. Ann Thorac Surg. 2004;78(4):1177–83.PubMedCrossRefPubMedCentralGoogle Scholar
  104. Martin JT, Federico JA, AA MK, et al. Prevention of delayed gastric emptying after esophagectomy: a single center’s experience with botulinum toxin. Ann Thorac Surg. 2009;87(6):1708–14.PubMedCrossRefPubMedCentralGoogle Scholar
  105. Matsuki A, Kanda T, Kosugi S, et al. Gastric tube interposition for corrosive esophagitis associated with pyloric stenosis. Surg Today. 2009;39(3):261–4.PubMedCrossRefPubMedCentralGoogle Scholar
  106. Matsumoto A, Omura N, Ishibashi Y, et al. Esophageal stricture caused by reflux esophagitis requiring subtotal esophagectomy: a case report. Esophagus. 2007;4:185–8.CrossRefGoogle Scholar
  107. Mendes LA, Connelly GP, PA MK, et al. Right coronary artery stenosis is an independent predictor of atrial fibrillation after coronary artery bypass surgery. J Am Coll Cardiol. 1995;25(1):198–202.PubMedCrossRefPubMedCentralGoogle Scholar
  108. Miller KB, Kaplan B, Shepherd RW. Severe tracheal compression causing respiratory failure after transhiatal esophagectomy. Ann Thorac Surg. 2010;89(3):977–9.PubMedCrossRefPubMedCentralGoogle Scholar
  109. Molina-Navarro C, Hosking SW, Hayward SJ, et al. Gastroaortic fistula as an early complication of esophagectomy. Ann Thorac Surg. 2001;72(5):1783–8.PubMedCrossRefPubMedCentralGoogle Scholar
  110. Morris JF, Koski A, Johnson LC. Spirometric standards for healthy nonsmoking adults. Am Rev Respir Dis. 1971;103(1):57–67.PubMedPubMedCentralGoogle Scholar
  111. Morton KA, Karwande SV, Davis RK, et al. Gastric emptying after gastric interposition for cancer of the esophagus or hypopharynx. Ann Thorac Surg. 1991;51(5):759–63.PubMedCrossRefPubMedCentralGoogle Scholar
  112. Nguven MT, Trop S, Soulellis C, et al. Esophageal-left atrial fistula: intraoperative diagnosis and management. Ann Thorac Surg. 2007;84(2):648–50.CrossRefGoogle Scholar
  113. Nguyen NT, Follette DM, Wolfe BM, et al. Comparison of minimally invasive esophagectomy with transthoracic and transhiatal esophagectomy. Arch Surg. 2000;135(8):920–5.PubMedCrossRefPubMedCentralGoogle Scholar
  114. Nguyen NT, Rudersdorf PD, Smith BR, et al. Management of Gastrointestinal leaks after minimally invasive esophagectomy: conventional treatments vs. endoscopic stenting. J Gastrointest Surg. 2011;15(11):1952–60.PubMedCrossRefPubMedCentralGoogle Scholar
  115. Odell JA, DeVault KR. Extended stent usage for persistent esophageal leak: should there be limits. Ann Thorac Surg. 2010;90(5):1707–8.PubMedCrossRefPubMedCentralGoogle Scholar
  116. Okamoto N, Ozawa S, Kitagawa Y, et al. Metachronous gastric carcinoma from a gastric tube after radical surgery for esophageal carcinoma. Ann Thorac Surg. 2004;77(4):1189–92.PubMedCrossRefPubMedCentralGoogle Scholar
  117. Okita R, Mukaida H, Takiyama W, et al. Successful surgical treatment of aortoesophageal fistula after esophagectomy. Ann Thorac Surg. 2005;79(3):1059–61.PubMedCrossRefPubMedCentralGoogle Scholar
  118. Okumura H, Uchikado Y, Owaki T, et al. Post-esophagectomy chylothorax successfully treated with the combination of thoracic duct clipping and octreotide administration. Esophagus. 2012;9:29–32.CrossRefGoogle Scholar
  119. Okuyama M, Saito R, Motoyama S, et al. Histological confirmation of healing of gastrobronchial fistula using a muscle flap. Ann Thorac Surg. 2002;73(4):1298–9.PubMedCrossRefPubMedCentralGoogle Scholar
  120. Orringer MB. Anterior mediastinal tracheostomy with and without cervical exenteration. Ann Thorac Surg. 1992;54(4):628–36.PubMedCrossRefPubMedCentralGoogle Scholar
  121. Pac M, Basoglu A, Yediyildiz S, et al. Gastrotracheal fistula as a result of radiotherapy transhiatal esophagectomy. Ann Thorac Surg. 1991;51(4):696–7.PubMedCrossRefPubMedCentralGoogle Scholar
  122. Palacio D, Mehran RJ, Marom EM. Esophageal luminal clot mimicking intramural esophageal hematoma. Ann Thorac Surg. 2011;91(2):e29.PubMedCrossRefPubMedCentralGoogle Scholar
  123. Parameswaran R, McNair A, Avery KN, et al. The role of health-related quality of life outcomes in clinical decision making in surgery for esophageal cancer: a systematic review. Ann Surg Oncol. 2008;15(9):2372–9.PubMedCrossRefPubMedCentralGoogle Scholar
  124. Pera M, Grande L, Gelabert M, et al. Epithelial cell hyperproliferation after biliopancreatic reflux into the esophagus of rats. Ann Thorac Surg. 1998;65(3):779–86.PubMedCrossRefPubMedCentralGoogle Scholar
  125. Pham TH, Perry KA, Enestvedt CK, et al. Decreased conduit perfusion measured by spectroscopy is associated with anastomotic complications. Ann Thorac Surg. 2011;91(2):380–5.PubMedCrossRefPubMedCentralGoogle Scholar
  126. Poje CP, Keane W, Atkins JP Jr, et al. Tracheo-gastric fistula following gastric pull-up. Ear Nose Throat J. 1991;70(12):848–50.PubMedPubMedCentralGoogle Scholar
  127. Pollock J. Radiation-induced secondary malignancy of the esophagus. Ann Thorac Surg. 2001;72(2):669.PubMedCrossRefPubMedCentralGoogle Scholar
  128. Raftopoulos Y, Landreneau RJ, Hayetian F, et al. Factors affecting quality of life after minimally invasive Heller myotomy for achalasia. J Gastrointest Surg. 2003;8(3):233–9.CrossRefGoogle Scholar
  129. Ramirez Schon G, Suarez Nieves A, Cebollero Marcucci J. Gastric vascular pedicle patch esophagoplasty for stricture. Ann Thorac Surg. 1989;48(3):356–8.PubMedCrossRefPubMedCentralGoogle Scholar
  130. Ricci D, Boffini M, Milanesi E, et al. Pericardium-esophageal fistula. Ann Thorac Surg. 2011;91(2):613.PubMedCrossRefPubMedCentralGoogle Scholar
  131. Ritchie AJ, Bowe P, Gibbons JR. Prophylactic digitalization for thoracotomy: a reassessment. Ann Thorac Surg. 1990;50(1):86–8.PubMedCrossRefPubMedCentralGoogle Scholar
  132. Ritchie AJ, Tolan M, Whiteside M, et al. Prophylactic digitalization fails to control dysrhythmia in thoracic esophageal operations. Ann Thorac Surg. 1993;55(1):86–8.PubMedCrossRefPubMedCentralGoogle Scholar
  133. Roberts JR, Wadsworth J. Recurrent laryngeal nerve monitoring during mediastinoscopy: predictors of injury. Ann Thorac Surg. 2007;83(2):388–92.PubMedCrossRefPubMedCentralGoogle Scholar
  134. Rutegrd M, Lagergren P. No influence of surgical volume on patients’ health-related quality of life after esophageal cancer resection. Ann Surg Oncol. 2008;15(9):2380–7.CrossRefGoogle Scholar
  135. Saadi A, Perentes JY, Gonzalez M, et al. Vacuum-assisted closure device: a useful tool in the management of severe intrathoracic infections. Ann Thorac Surg. 2011;91(5):1582–9.PubMedCrossRefPubMedCentralGoogle Scholar
  136. Saeki H, Ishimura H, Higashi H, et al. Postoperative management using intensive patient-controlled epidural analgesia and early rehabilitation after an esophagectomy. Surg Today. 2009;39(6):476–80.PubMedCrossRefPubMedCentralGoogle Scholar
  137. Salameh JR, Aru GM, Bolton W, et al. Electrostimulation for intractable delayed emptying of intrathoracic stomach after esophagectomy. Ann Thorac Surg. 2008;85(4):1417–9.PubMedCrossRefPubMedCentralGoogle Scholar
  138. Santin B, Kulwicki A, Price P. Mortality rate associated with 56 consecutive esophagectomies performed at a “low-volume” hospital: is procedure volume as important as we are trying to make it. J Gastrointest Surg. 2008;12(8):1346–50.PubMedCrossRefPubMedCentralGoogle Scholar
  139. Santos GH. Pulmonary complications following esophagectomy. Ann Thorac Surg. 2003;75(2):634–5.PubMedCrossRefPubMedCentralGoogle Scholar
  140. Schrder W, Stippel D, Lacher M, et al. Does continuous mucosal partial carbon dioxide pressure measurement predict leakage of intrathoracic esophagogastrostomy. Ann Thorac Surg. 2002a;74(6):1917–22.CrossRefGoogle Scholar
  141. Schrder W, Zahringer M, Stippel D, et al. Does celiac trunk stenosis correlate with anastomotic leakage of esophagogastrostomy after esophagectomy. Dis Esophagus. 2002b;15(3):232–6.CrossRefGoogle Scholar
  142. Schuchert MJ, Luketich JD, Fernando HC. Complications of minimally invasive esophagectomy. Semin Thorac Cardiovasc Surg. 2004;16(2):133–41.PubMedCrossRefPubMedCentralGoogle Scholar
  143. Shiraishi T, Kawahara K, Shirakusa T, et al. Stenting for airway obstruction in the carinal region. Ann Thorac Surg. 1998;66(6):1925–9.PubMedCrossRefPubMedCentralGoogle Scholar
  144. Song SW, Lee HS, Kim JH, et al. Readmission to intensive care unit after initial recovery from major thoracic oncology surgery. Ann Thorac Surg. 2007;84(6):1838–46.PubMedCrossRefPubMedCentralGoogle Scholar
  145. St Julien J, Putnam JB Jr, Nesbitt JC, et al. Successful treatment of atrioesophageal fistula by cervical esophageal ligation and decompression. Ann Thorac Surg. 2011;91(6):85–6.CrossRefGoogle Scholar
  146. Stal JM, Hanley PJ, Darling GE. Gastrobrochial fistula: an unusual complication of esophagectomy. Ann Thorac Surg. 1994;58(3):886–7.PubMedCrossRefPubMedCentralGoogle Scholar
  147. Steinberg JS, Zelenkofske S, Wong SC, et al. Value of the P-wave signal-averaged ECG for predicting atrial fibrillation after cardiac surgery. Circulation. 1993;88(6):2618–22.PubMedCrossRefPubMedCentralGoogle Scholar
  148. Suzuki S, Morimatsu H, Omori E, et al. Response to surgical stress after esophagectomy: Gene expression of heat shock protein 70, toll-like receptor 4, tumor necrosis factor and inducible nitric oxide synthase. Mol Med Rep. 2010;3(5):765–9.PubMedPubMedCentralGoogle Scholar
  149. Symbas PN, McKeown PP, Hatcher CR Jr, et al. Tracheoesophageal fistula from carcinoma of the esophagus. Ann Thorac Surg. 1984;38(4):382–6.PubMedCrossRefPubMedCentralGoogle Scholar
  150. Tanaka Y, Maniwa Y, Yoshimura M, et al. Successful treatment of descending necrotizing mediastinitis. Gen Thorac Cardiovasc Surg. 2007;55(9):366–9.PubMedCrossRefPubMedCentralGoogle Scholar
  151. Tsutsui S, Moriguchi S, Morita M, et al. Multivariate analysis of postoperative complications after esophageal resection. Ann Thorac Surg. 1992;53(6):1052–6.PubMedCrossRefPubMedCentralGoogle Scholar
  152. Turaga KK, Shah KU, Neill EO, et al. Does laparoscopic surgery decrease the risk of atrial fibrillation after foregut surgery. Surg Endosc. 2009;23(1):204–8.PubMedCrossRefPubMedCentralGoogle Scholar
  153. Turnbull AD, Carlon G, Howland WS, et al. High-frequency jet ventilation in major airway or pulmonary disruption. Ann Thorac Surg. 1981;32(5):468–74.PubMedCrossRefPubMedCentralGoogle Scholar
  154. Udagawa H, Ueno M, Kinoshita Y. Rationale for video-assisted radical esophagectomy. Gen Thorac Cardiovasc Surg. 2009;57(3):127–31.PubMedPubMedCentralCrossRefGoogle Scholar
  155. Unemura Y, Ishida Y, Suzuki Y, et al. Impact of prophylactic mupirocin for radical esophagectomy. J Infect Chemother. 2006;12(5):257–63.PubMedCrossRefPubMedCentralGoogle Scholar
  156. Vallbhmer D, Hölscher AH, Herbold T, et al. Diaphragmatic hernia after conventional or laparoscopic-assisted transthoracic esophagectomy. Ann Thorac Surg. 2007;84(6):1847–52.CrossRefGoogle Scholar
  157. Vaporciyan AA, Reed CE, Erikson C, et al. Factors affecting interest in cardiothoracic surgery: survey of North American general surgery residents. Ann Thorac Surg. 2009;87(5):1351–9.PubMedCrossRefPubMedCentralGoogle Scholar
  158. Veeramootoo D, Parameswaran R, Krishnadas R, et al. Classification and early recognition of gastric conduit failure after minimally invasive esophagectomy. Surg Endosc. 2009;23(9):2110–6.PubMedCrossRefPubMedCentralGoogle Scholar
  159. Voelter V, Schuhmacher C, Busch R, et al. Incidence of anemia in patients receiving neoadjuvant chemotherapy for locally advanced esophagogastric cancer. Ann Thorac Surg. 2004;78(3):1037–41.PubMedCrossRefPubMedCentralGoogle Scholar
  160. Von Knorring J, Lepantalo M, Lindgren L, et al. Cardiac arrhythmias and myocardial ischemia after thoracotomy for lung cancer. Ann Thorac Surg. 1992;53(4):642–7.CrossRefGoogle Scholar
  161. Walsh GL, Nesbitt JC. Tumor implants after thoracoscopic resections of metastatic sarcoma. Ann Thorac Surg. 1995;59(1):215–6.PubMedCrossRefPubMedCentralGoogle Scholar
  162. Wang H, Tan LJ, Feng MX, et al. Comparison of the short-term health-related quality of life in patients with esophageal cancer with different routes of gastric tube reconstruction after minimally invasive esophagectomy. Qual Life Res. 2011;20:179–89.PubMedCrossRefPubMedCentralGoogle Scholar
  163. Wei JY. Age and the cardiovascular system. N Engl J Med. 1992;327(24):1735–9.PubMedCrossRefPubMedCentralGoogle Scholar
  164. Wlodarczyk J, Olechnowicz H, Kocon P. Esophago-pericardial fistula during the course of primary esophageal carcinoma. Ann Thorac Surg. 2008;86(6):1967–9.PubMedCrossRefPubMedCentralGoogle Scholar
  165. Wojcik J, Grodzki T, Kubisa B, et al. Stricture caused by a plastic vascular clip used during an operation of minimally invasive esophagectomy. Interact Cardiovasc Thorac Surg. 2011;13(4):435–6.PubMedCrossRefPubMedCentralGoogle Scholar
  166. Xue L, Pan T, Xu Z, et al. Multi-factor investigation of early postoperative cardiac arrhythmia for elderly patients with esophageal or cardiac carcinoma. World J Surg. 2009;33(12):2615–9.PubMedCrossRefPubMedCentralGoogle Scholar
  167. Yim AP. Video assisted thoracoscopic suturing of apical bullae, an alternative to staple resection in the management of primary spontaneous pneumothorax. Surg Endosc. 1995;9(9):1013–6.PubMedCrossRefPubMedCentralGoogle Scholar
  168. Yim AP, Ho JKS. 100 consecutive cases of video assisted thoracoscopic surgery for primary spontaneous pneumothorax. Surg Endosc. 1995;9(3):332–6.PubMedCrossRefPubMedCentralGoogle Scholar
  169. Yim APC, Ho JKS, Lee TW, et al. Thoracoscopic management of pleural effusion revisited. Aust N Z J Surg. 1995a;65(5):308–11.PubMedCrossRefPubMedCentralGoogle Scholar
  170. Yim AP, Low JM, Ng SK, et al. Video assisted thoracoscopic surgery in the paediatric population. J Paediatr Child Health. 1995b;31(3):192–6.PubMedCrossRefPubMedCentralGoogle Scholar
  171. Yim AP, Ko KM, Chau WS, et al. Video assisted thoracoscopic anatomical lung resections. The initial Hong Kong experience. Chest. 1996a;109(1):13–7.PubMedCrossRefPubMedCentralGoogle Scholar
  172. Yim AP, Ko KM, Ma CC, et al. Thoracoscopic lobectomy for benign diseases. Chest. 1996b;109(2):554–6.PubMedCrossRefPubMedCentralGoogle Scholar
  173. Yuan Y, Hu Y, Xie T, et al. Myxedema coma after esophagectomy. Ann Thorac Surg. 2010;90(1):295–7.PubMedCrossRefPubMedCentralGoogle Scholar
  174. Zehr KJ, Dawson FB, Yang SC, et al. Standardized clinical care pathways for major thoracic cases reduce hospital costs. Ann Thorac Surg. 1998;66(3):914–9.PubMedCrossRefPubMedCentralGoogle Scholar
  175. Zieren HU, Müller JM, Jacobi CA, et al. Should a pyloroplasty be carried out in stomach transposition after subtotal esophagectomy with esophao-gastric anastomosis in the neck? A prospective randomized study. Chirurg. 1995;66(4):319–25.PubMedPubMedCentralGoogle Scholar
  176. Zingg U, Langton C, Addison B, et al. Risk prediction scores for postoperative mortality after esophagectomy: validation of different models. J Gastrointest Surg. 2009;13(4):611–8.PubMedCrossRefPubMedCentralGoogle Scholar
  177. Zingg U, Smithers BM, Gotley DC, et al. Factors associated with postoperative pulmonary morbidity after esophagectomy for cancer. Ann Surg Oncol. 2011;18(5):1460–8.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. and Huazhong University of Science and Technology Press 2018

Authors and Affiliations

  • Jun Yi
    • 1
  1. 1.Department of Cardiothoracic SurgeryThe First People’s Hospital of Jing MenJing MenChina

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