Endoscopic Treatment of Esophageal Varices: Takase Method
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Endoscopic injection sclerotherapy (EIS), using the Takase method is now widely accepted and used to treat esophageal varices.
Intravariceal injection of 5% ethanolamine oleate with contrast iopamidol embolizes the varices along with blood supply routes. Portal hemodynamics and liver function are not affected after EIS. The recurrence rates of esophageal varices at 2 years after EIS with complete and incomplete embolization of blood supply routes were 7% and 70%, respectively (p < 0.05). Because of this result, we consider the complete embolization of varices and their blood supply routes with EIS to be the first-choice treatment for esophageal varices to diminish the variceal recurrence rate.
KeywordsEndoscopic injection sclerotherapy Esophagogastric varices Blood supply route 5% Ethanolamine oleate with iopamidol
I thank Dr. Niranjan Sharma PhD, Mornington Health Center, Dunedin, New Zealand, for helpful comments.