Notarization of Knowledge Retrieval from Biomedical Repositories Using Blockchain Technology

  • P. Mytis-Gkometh
  • G. DrosatosEmail author
  • P. S. Efraimidis
  • E. Kaldoudi
Conference paper
Part of the IFMBE Proceedings book series (IFMBE, volume 66)


Biomedical research and clinical decision depend increasingly on a number of authoritative databases, mostly public and continually enriched via peer scientific contributions. Given the dynamic nature of data and their usage in the sensitive domain of biomedical science, it is important to ensure retrieved data integrity and non-repudiation, that is, ensure that retrieved data cannot be modified after retrieval and that the database cannot validly deny that the particular data has been provided as a result of a specific query. In this paper, we propose the use of blockchain technology in combination with digital signatures to create smart digital contracts to seal the query and the respective results each time a third-party requests evidence from a reference biomedical database. The feasibility of the proposed approach is demonstrated using a real blockchain infrastructure and a publicly available medical risk factor reference repository.


Biomedical repositories Cryptographic techniques Blockchain Integrity Non-repudiation 



This work was partly supported by the European Commission FP7-ICT project CARRE (Grant No. 611140).

Conflict of Interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • P. Mytis-Gkometh
    • 1
  • G. Drosatos
    • 2
    Email author
  • P. S. Efraimidis
    • 1
  • E. Kaldoudi
    • 2
  1. 1.Department of Electrical and Computer EngineeringDemocritus University of ThraceKimmeria, XanthiGreece
  2. 2.School of MedicineDemocritus University of ThraceAlexandroupoliGreece

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