Ambient Air Pollution and Morbidity in Chinese

  • Li-Wen Hu
  • Wayne R. Lawrence
  • Yimin Liu
  • Bo-Yi Yang
  • Xiao-Wen Zeng
  • Wen Chen
  • Guang-Hui Dong
Chapter
First Online:
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1017)

Abstract

The rapid economic growth in China is coupled with a severe ambient air pollution, which poses a huge threat to human health and the sustainable development of social economy. The rapid urbanization and industrialization over the last three decades have placed China as one of countries with the greatest disease burden in world. Notably, the prevalence rate of chronic noncommunicable diseases (CND), including respiratory diseases, CVD, and stroke, in 2010 reaches 16.9%. The continuous growth of the incidence of CND urgent needs for effective regulatory action for health protection. This study aims to evaluate the impact of rapid urbanization on status of ambient air pollution and associated adverse health effects on the incidence and the burden of CND and risk assessment. Our findings would be greatly significant in the prediction of the risk of ambient air pollution on CND and for evidence-based policy making and risk management in China.

Keywords

Ambient air pollution Mortality Chinese Adults 
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Notes

Acknowledgments

This study was funded by grants from the Major Program of National Natural Science Foundation of China (91543208), the National Natural Science Foundation of China (No. 81472936, 81673127, and 81673128), the National Key Research and Development Program of China (2016YFC0207000), the Guangdong Province Natural Science Foundation (2014A050503027), and the Fundamental Research Funds for the Central Universities (No. 16ykzd02, 17ykpy16).

References

  1. 1.
    Arnold C. Disease burdens associated with PM2.5 exposure: how a new model provided global estimates. Environ Health Perspect. 2014;122(4):A111.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Burnett RT1, Pope CA 3rd, Ezzati M, Olives C, Lim SS, Mehta S, Shin HH, Singh G, Hubbell B, Brauer M, Anderson HR, Smith KR, Balmes JR, Bruce NG, Kan H, Laden F, Prüss-Ustün A, Turner MC, Gapstur SM, Diver WR, Cohen A. An integrated risk function for estimating the global burden of disease attributable to ambient fine particulate matter exposure. Environ Health Perspect. 2014;122(4):397–403.PubMedPubMedCentralGoogle Scholar
  3. 3.
    Brauer M, Freedman G, Frostad J, van Donkelaar A, Martin RV, Dentener F, van Dingenen R, Estep K, Amini H, Apte JS, Balakrishnan K, Barregard L, Broday D, Feigin V, Ghosh S, Hopke PK, Knibbs LD, Kokubo Y, Liu Y, Ma S, Morawska L, Sangrador JL, Shaddick G, Anderson HR, Vos T, Forouzanfar MH, Burnett RT, Cohen A. Ambient air pollution exposure estimation for the global burden of disease 2013. Environ SciTechnol. 2016;50(1):79–88.CrossRefGoogle Scholar
  4. 4.
    Cao C, Jiang W, Wang B, Fang J, Lang J, Tian G, Jiang J, Zhu TF. Inhalable microorganisms in Beijing's PM2.5 and PM10 pollutants during a severe smog event. Environ SciTechnol. 2014;48(3):1499–507.CrossRefGoogle Scholar
  5. 5.
    Cassee FR, Héroux ME, Gerlofs-Nijland ME, Kelly FJ. Particulate matter beyond mass: recent health evidence on the role of fractions, chemical constituents and sources of emission. Inhal Toxicol. 2013;25:802–12.CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Chen J, Zhao Q, Liu BB, Wang J, Xu HB, Zhang Y, Song XM, He B, Huang W. Airway oxidative stress and inflammation markers in chronic obstructive pulmonary diseases (COPD) patients are linked with exposure to traffic-related air pollution: a panel study. Zhonghua Yu Fang Yi XueZaZhi. 2016;50(5):411–7.Google Scholar
  7. 7.
    Chen S, Gu Y, Qiao L, Wang C, Song Y, Bai C, Sun Y, Ji H, Zhou M, Wang H, Chen R, Kan H. Fine particulate constituents and lung dysfunction: a time-series panel study. Environ SciTechnol. 2017;51(3):1687–94.CrossRefGoogle Scholar
  8. 8.
    Chen G, Zhang W, Li S, Williams G, Liu C, Morgan GG, Jaakkola JJ, Guo Y. Is short-term exposure to ambient fine particles associated with measles incidence in China? A multi-city study. Environ Res. 2017;156:306–11.CrossRefPubMedGoogle Scholar
  9. 9.
    Cheng MH, Chiu HF, Yang CY. Coarse particulate air pollution associated with increased risk of hospital admissions for respiratory diseases in a Tropical City, Kaohsiung, Taiwan. Int J Environ Res Public Health. 2015;12(10):13053–68.CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Cohen AJ, Brauer M, Burnett R, Anderson HR, Frostad J, Estep K, Balakrishnan K, Brunekreef B, Dandona L, Dandona R, Feigin V, Freedman G, Hubbell B, Jobling A, Kan H, Knibbs L, Liu Y, Martin R, Morawska L, Pope CA 3rd, Shin H, Straif K, Shaddick G, Thomas M, van Dingenen R, van Donkelaar A, Vos T, Murray CJ, Forouzanfar MH. Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet. 2017; doi: 10.1016/S0140-6736(17)30505-6.
  11. 11.
    Dockery DW, Pope CA 3rd, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG Jr, Speizer FE. An association between air pollution and mortality in six U.S. cities. N Engl J Med. 1993;329(24):1753–9.CrossRefPubMedGoogle Scholar
  12. 12.
    Dong GH, Zhang P, Sun B, Zhang L, Chen X, Ma N, Yu F, Guo H, Huang H, Lee YL, Tang N, Chen J. Long-term exposure to ambient air pollution and respiratory disease mortality in Shenyang, China: a 12-year population-based retrospective cohort study. Respiration. 2012;84(5):360–8.CrossRefPubMedGoogle Scholar
  13. 13.
    Dong GH, Qian Z, Wang J, Chen W, Ma W, Trevathan E, Xaverius PK, DeClue R, Wiese A, Langston M, Liu MM, Wang D, Ren WH. Association between ambient air pollution and prevalence of stroke and cardiovascular diseases in 33 Chinese communities. Atmos Environ. 2013;77:968–73.CrossRefGoogle Scholar
  14. 14.
    Dong GH, Qian ZM, Xaverius PK, Trevathan E, Maalouf S, Parker J, Yang L, Liu MM, Wang D, Ren WH, Ma W, Wang J, Zelicoff A, Fu Q, Simckes M. Association between long-term air pollution and increased blood pressure and hypertension in China. Hypertension. 2013;61(3):578–84.CrossRefPubMedGoogle Scholar
  15. 15.
    Emmanuel SC. Impact to lung health of haze from forest fires: the Singapore experience. Respirology. 2000;5:175–82.CrossRefPubMedGoogle Scholar
  16. 16.
    Feng C, Li J, Sun W, Zhang Y, Wang Q. Impact of ambient fine particulate matter (PM2.5) exposure on the risk of influenza-like-illness: a time-series analysis in Beijing, China. Environ Health. 2016;15:17.CrossRefPubMedPubMedCentralGoogle Scholar
  17. 17.
    GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the global burden of disease study 2015. Lancet. 2016;388:1659–724.CrossRefGoogle Scholar
  18. 18.
    Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Magid D, Marcus GM, Marelli A, Matchar DB, DK MG, Mohler ER, Moy CS, Mussolino ME, Nichol G, Paynter NP, Schreiner PJ, Sorlie PD, Stein J, Turan TN, Virani SS, Wong ND, Woo D, Turner MB. American Heart Association statistics C, stroke statistics S. Executive summary: heart disease and stroke statistics—2013 update: a report from the American Heart Association. Circulation. 2013;127(1):143–52.CrossRefPubMedGoogle Scholar
  19. 19.
    Guan WJ, Zheng XY, Chung K, Zhong NS. Impact of air pollution on the burden of chronic respiratory diseases in China: time for urgent action. Lancet. 2016;388(10054):1939–51.CrossRefPubMedGoogle Scholar
  20. 20.
    Harrison RM, Bousiotis D, Mohorjy AM, Alkhalaf AK, Shamy M, Alghamdi M, Khoder M, Costa M. Health risk associated with airborne particulate matter and its components in Jeddah, Saudi Arabia. Sci Total Environ. 2017;590–591:531–9.CrossRefPubMedGoogle Scholar
  21. 21.
    Hettige HMM. Industrial pollution in economic development: the environmental Kuznets curve revisited. J Dev Econ. 2000;62(2):445–76.CrossRefGoogle Scholar
  22. 22.
    Huang J, Deng F, Wu S, Zhao Y, Shima M, Guo B, Liu Q, Guo X. Acute effects on pulmonary function in young healthy adults exposed to traffic-related air pollution in semi-closed transport hub in Beijing. Environ Health Prev Med. 2016;21(5):312–20.CrossRefPubMedPubMedCentralGoogle Scholar
  23. 23.
    Huang L, Zhou L, Chen J, Chen K, Liu Y, Chen X, Tang F. Acute effects of air pollution on influenza-like illness in Nanjing, China: a population-based study. Chemosphere. 2016;147:180–7.CrossRefPubMedGoogle Scholar
  24. 24.
    Huang R, Bian G, He T, Chen L, Xu G. Effects of meteorological parameters and PM10 on the incidence of hand, foot, and mouth disease in children in China. Int J Environ Res Public Health 2016; 13(5).Google Scholar
  25. 25.
    Jang JH, Lee JH, Je MK, Cho MJ, Bae YM, Son HS, Ahn I. Correlations between the incidence of national notifiable infectious diseases and public OpenData, including meteorological factors and medical facility resources. J Prev Med Public Health. 2015;48(4):203–15.CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Kan H, Chen B. A case-crossover analysis for air pollution and daily mortality in Shanghai. J Occup Health. 2003;45:119–24.CrossRefPubMedGoogle Scholar
  27. 27.
    Ko FW, Tam W, Wong TW, Chan DP, Tung AH, Lai CK, Hui DS. Temporal relationship between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Hong Kong. Thorax. 2007;62:780–5.CrossRefPubMedPubMedCentralGoogle Scholar
  28. 28.
    Kuehn BM. WHO: more than 7 million air pollution deaths each year. JAMA. 2014;311(15):1486.CrossRefPubMedGoogle Scholar
  29. 29.
    Lawes CM, Hoorn SV, Rodgers A. Global burden of blood-pressure-related disease, 2001. Lancet. 2008;371:1513–8.CrossRefPubMedGoogle Scholar
  30. 30.
    Leitte AM, Schlink U, Herbarth O, Wiedensohler A, Pan XC, Hu M, Richter M, Wehner B, Tuch T, Wu Z, Yang M, Liu L, Breitner S, Cyrys J, Peters A, Wichmann HE, Franck U. Size-segregated particle number concentrations and respiratory emergency room visits in Beijing, China. Environ Health Perspect. 2011;119(4):508–13.Google Scholar
  31. 31.
    Li MH, Fan LC, Mao B, Yang JW, Choi AM, Cao WJ, Xu JF. Short-term exposure to ambient fine particulate matter increases hospitalizations and mortality in COPD: a systematic review and meta-analysis. Chest. 2016;149(2):447–58.CrossRefPubMedGoogle Scholar
  32. 32.
    Li M, Qian Z, Vaughn M, Boutwell B, Ward P, Lu T, Lin S, Zhao Y, Zeng XW, Liu RQ, Qin XD, Zhu Y, Chen W, Dong GH. Sex-specific difference of the association between ambient air pollution and the prevalence of obesity in Chinese adults from a high pollution range area: 33 communities Chinese health study. Atmos Environ. 2015;117:227–33.CrossRefGoogle Scholar
  33. 33.
    Lin H, Guo Y, Zheng Y, Di Q, Liu T, Xiao J, Li X, Zeng W, Cummings-Vaughn LA, Howard SW, Vaughn MG, Qian ZM, Ma W, Wu F. Long-term effects of ambient PM2.5 on hypertension and blood pressure and attributable risk among older Chinese adults. Hypertension. 2017;69(5):806–12.CrossRefPubMedGoogle Scholar
  34. 34.
    Lin H, Guo Y, Di Q, Zheng Y, Kowal P, Xiao J, Liu T, Li X, Zeng W, Howard SW, Nelson EJ, Qian Z, Ma W, Wu F. Ambient PM2.5 and stroke: effect modifiers and population attributable risk in six low- and middle-income countries. Stroke. 2017;48(5):1191–7.CrossRefPubMedGoogle Scholar
  35. 35.
    Liu C, Chen R, Zhao Y, Ma Z, Bi J, Liu Y, Meng X, Wang Y, Chen X, Li W, Kan H. Associations between ambient fine particulate air pollution and hypertension: a nationwide cross-sectional study in China. Sci Total Environ. 2017;584–585:869–74.CrossRefPubMedGoogle Scholar
  36. 36.
    Liu L, Breitner S, Schneider A, Cyrys J, Brüske I, Franck U, Schlink U, Marian Leitte A, Herbarth O, Wiedensohler A, Wehner B, Pan X, Wichmann HE, Peters A. Size-fractioned particulate air pollution and cardiovascular emergency room visits in Beijing, China. Environ Res. 2013;121:52–63.CrossRefPubMedGoogle Scholar
  37. 37.
    Liu ST, Liao CY, Kuo CY, Kuo HW. The effects of PM2.5 from Asian dust storms on emergency room visits for cardiovascular and respiratory diseases. Int J Environ Res Public Health 2017; 14(4).Google Scholar
  38. 38.
    Mathers CD, Sadana R, Salomon JA, Murray CJ, Lopez AD. Healthy life expectancy in 191 countries, 1999. Lancet. 2001;357(9269):1685–91.CrossRefPubMedGoogle Scholar
  39. 39.
    Ma Y, Zhang H, Zhao Y, Zhou J, Yang S, Zheng X, Wang S. Short-term effects of air pollution on daily hospital admissions for cardiovascular diseases in western China. Environ SciPollut Res Int. 2017; doi: 10.1007/s11356-017-8971-z.
  40. 40.
    Mendis S, Puska P, Norrving B. Global Atlas on cardiovascular disease prevention and control. Published by the World Health Organization in collaboration with the World Heart Federation and the World Strike Organization, 2011. ISBN 978 92 4 156437 3.
  41. 41.
    Nemmar A, Vanbilloen H, Hoylaerts MF, Hoet PH, Verbruggen A, Nemery B. Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster. Am J Respir Crit Care Med. 2001;164(9):1665–8.CrossRefPubMedGoogle Scholar
  42. 42.
    Nemmar A, Hoet PH, Vanquickenborne B, Dinsdale D, Thomeer M, Hoylaerts MF, Vanbilloen H, Mortelmans L, Nemery B. Passage of inhaled particles into the blood circulation in humans. Circulation. 2002;105(4):411–4.CrossRefPubMedGoogle Scholar
  43. 43.
    Ni Y, Wu S, Ji W, Chen Y, Zhao B, Shi S, Tu X, Li H, Pan L, Deng F, Guo X. The exposure metric choices have significant impact on the association between short-term exposure to outdoor particulate matter and changes in lung function: findings from a panel study in chronic obstructive pulmonary disease patients. Sci Total Environ. 2016;542(Pt A):264–70.CrossRefPubMedGoogle Scholar
  44. 44.
    Pan Q, Yu Y, Tang Z, Xi M, Zang G. Haze, a hotbed of respiratory-associated infectious diseases, and a new challenge for disease control and prevention in China. Am J Infect Control. 2014;42(6):688.CrossRefPubMedGoogle Scholar
  45. 45.
    Peng CQ, Cai JF, Yu SY, Cao ZJ, Liao YX, Liu N, He L, Zhang L, Zheng J, Shi XM, Cheng JQ. Impact of PM2.5 on daily outpatient numbers for respiratory diseases in Shenzhen, China. Zhonghua Yu Fang Yi XueZaZhi. 2016;50(10):874–9.Google Scholar
  46. 46.
    Ping J. Influence of hazy weather on patient presentation with respiratory diseases in Beijing, China. Asian Pac J Cancer Prev. 2015;16(2):607–11.CrossRefPubMedGoogle Scholar
  47. 47.
    Pope CA 3rd, Dockery DW. Air pollution and life expectancy in China and beyond. Proc Natl Acad Sci U S A. 2013;110(32):12861–2.CrossRefPubMedPubMedCentralGoogle Scholar
  48. 48.
    Prabhakaran D, Roy A, Praveen PA, Ramakrishnan L, Gupta R, Amarchand R, Kondal D, Singh K, Sharma M, Shukla DK, Tandon N, Reddy KS, Krishnan A. 20-year trend of cardiovascular disease risk factors: urban and rural National Capital Region of Delhi. India Glob Heart. 2017; doi: 10.1016/j.gheart.2016.11.004.
  49. 49.
    Qin XD, Qian Z, Vaughn MG, Trevathan E, Emo B, Paul G, Ren WH, Hao YT, Dong GH. Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: a large population based cross sectional study. Sci Total Environ. 2015;529:243–8.CrossRefPubMedGoogle Scholar
  50. 50.
    Qiu H, Yu IT, Tian L, Wang X, Tse LA, Tam W, Wong TW. Effects of coarse particulate matter on emergency hospital admissions for respiratory diseases: a time-series analysis in Hong Kong. Environ Health Perspect. 2012;120(4):572–6.CrossRefPubMedPubMedCentralGoogle Scholar
  51. 51.
    Qiu H, Yu IT, Wang X, Tian L, Tse LA, Wong TW. Cool and dry weather enhances the effects of air pollution on emergency IHD hospital admissions. Int J Cardiol. 2013;168(1):500–5.CrossRefPubMedGoogle Scholar
  52. 52.
    McDonald RA. Health effects of carbon-containing particulate matter: focus on sources and recent research program results. Crit Rev Toxicol. 2016;46(2):97–137.CrossRefPubMedGoogle Scholar
  53. 53.
    Sedlmaier N, Hoppenheidt K, Krist H, Lehmann S, Lang H, Buttner M. Generation of avian influenza virus (AIV) contaminated fecal fine particulate matter (PM2.5): genome and infectivity detection and calculation of immission. Vet Microbiol. 2009;139(1–2):156–64.CrossRefPubMedGoogle Scholar
  54. 54.
    Sheppard L, Burnett RT, Szpiro AA, Kim SY, Jerrett M, Pope CA, Brunekreef B. Confounding and exposure measurement error in air pollution epidemiology. Air Qual Atmos Health. 2012;5(2):203–16.Google Scholar
  55. 55.
    Shi J, Chen R, Yang C, Lin Z, Cai J, Xia Y, Wang C, Li H, Johnson N, Xu X, Zhao Z, Kan H. Association between fine particulate matter chemical constituents and airway inflammation: a panel study among healthy adults in China. Environ Res. 2016;150:264–8.CrossRefPubMedGoogle Scholar
  56. 56.
    Stone AC, Nici L. Other systemic manifestations of chronic obstructive pulmonary disease. Clin Chest Med. 2007;28(3):553–7.CrossRefPubMedGoogle Scholar
  57. 57.
    Su C, Breitner S, Schneider A, Liu L, Franck U, Peters A, Pan X. Short-term effects of fine particulate air pollution on cardiovascular emergency room visits: a time-series study in Beijing. China Int Arch Occup Environ Health. 2016;89(4):641–57.CrossRefPubMedGoogle Scholar
  58. 58.
    Sun Q, Hong X, Wold LE. Cardiovascular effects of ambient particulate air pollution exposure. Circulation. 2010;121(25):2755–65.CrossRefPubMedPubMedCentralGoogle Scholar
  59. 59.
    Sun S, Qiu H, Ho KF, Tian L. Chemical components of respirable particulate matter associated with emergency hospital admissions for type 2 diabetes mellitus in Hong Kong. Environ Int. 2016;97:93–9.CrossRefPubMedGoogle Scholar
  60. 60.
    Tam WW, Wong TW, Wong AH, Hui DS. Effect of dust storm events on daily emergency admissions for respiratory diseases. Respirology. 2012;17(1):143–8.CrossRefPubMedGoogle Scholar
  61. 61.
    Tian L, Ho KF, Wang T, Qiu H, Pun VC, Chan CS, Louie PK, Yu IT. Ambient carbon monoxide and the risk of hospitalization due to chronic obstructive pulmonary disease. Am J Epidemiol. 2014;180:1159–67.CrossRefPubMedGoogle Scholar
  62. 62.
    Tian L, Qiu H, Pun VC, Ho KF, Chan CS, Yu IT. Carbon monoxide and stroke: a time series study of ambient air pollution and emergency hospitalizations. Int J Cardiol. 2015;201:4–9.CrossRefPubMedGoogle Scholar
  63. 63.
    Tao Y, Huang W, Huang X, Zhong L, Lu SE, Li Y, Dai L, Zhang Y, Zhu T. Estimated acute effects of ambient ozone and nitrogen dioxide on mortality in the Pearl River Delta of southern China. Environ Health Perspect. 2012;120:393–8.CrossRefPubMedGoogle Scholar
  64. 64.
    U. S. EPA. Guidelines for exposure assessment. Washington, DC. 1992.Google Scholar
  65. 65.
    Vasilatou V, Diapouli E, Abatzoglou D, Bakeas EB, Scoullos M, Eleftheriadis K. Characterization of PM2.5 chemical composition at the Demokritos suburban station, in Athens Greece. The influence of Saharan dust. Environ SciPollut Res Int. 2017;24(12):11836–46.CrossRefGoogle Scholar
  66. 66.
    Wei Y, Zhang JJ, Li Z, Gow A, Chung KF, Hu M, Sun Z, Zeng L, Zhu T, Jia G, Li X, Duarte M, Tang X. Chronic exposure to air pollution particles increases the risk of obesity and metabolic syndrome: findings from a natural experiment in Beijing. FASEB J. 2016;30(6):2115–22.CrossRefPubMedGoogle Scholar
  67. 67.
    Wu S, Deng F, Huang J, Wang X, Qin Y, Zheng C, Wei H, Shima M, Guo X. Does ambient temperature interact with air pollution to alter blood pressure? A repeated-measure study in healthy adults. J Hypertens. 2015;33(12):2414–21.CrossRefPubMedGoogle Scholar
  68. 68.
    Wu S, Deng F, Wei H, Huang J, Wang X, Hao Y, Zheng C, Qin Y, Lv H, Shima M, Guo X. Association of cardiopulmonary health effects with source-appointed ambient fine particulate in Beijing, China: a combined analysis from the Healthy Volunteer Natural Relocation (HVNR) study. Environ SciTechnol. 2014;48(6):3438–48.CrossRefGoogle Scholar
  69. 69.
    Wu S, Deng F, Hao Y, Shima M, Wang X, Zheng C, Wei H, Lv H, Lu X, Huang J, Qin Y, Guo X. Chemical constituents of fine particulate air pollution and pulmonary function in healthy adults: the Healthy Volunteer Natural Relocation study. J Hazard Mater. 2013;260:183–91.CrossRefPubMedGoogle Scholar
  70. 70.
    Wang W, Ying Y, Wu Q, Zhang H, Na D, Xiao W. A GIS-based spatial correlation analysis for ambient air pollution and AECOPD hospitalizations in Jinan, China. Respir Med. 2015;109(3):372–8.CrossRefPubMedGoogle Scholar
  71. 71.
    Wang X, Li G, Jin X, Mu J, Pan J, Liang F, Tian L, Chen S, Guo Q, Dong W, Pan X. Study of relationship between atmospheric fine particulate matter concentration and one grade a tertiary hospital emergency room visits during 2012 and 2013 in Beijing. Zhonghua Yu Fang Yi Xue Za Zhi. 2016;50(1):73–8.Google Scholar
  72. 72.
    World Health Organization. Global health risks: mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization; 2009. (NLM classification: WA 105). http://www.who.int/ Google Scholar
  73. 73.
    Wong ND, Dede J, Chow VH, Wong KS, Franklin SS. Global cardiovascular risk associated with hypertension and extent of treatment and control according to risk group. Am J Hypertens. 2012;25:561–7.CrossRefPubMedGoogle Scholar
  74. 74.
    Wong TW, Lau TS, Yu TS, Neller A, Wong SL, Tam W, Pang SW. Air pollution and hospital admissions for respiratory and cardiovascular diseases in Hong Kong. Occup Environ Med. 1999;56(10):679–83.CrossRefPubMedPubMedCentralGoogle Scholar
  75. 75.
    Wu Y, Zhao F, Qian X, Xu G, He T, Shen Y, Cai Y. Relationship beween sulfur dioxide pollution and upper respiratory outpatients in Jiangbei. Ningbo Wi Sheng Yan Jiu. 2015;44(4):565–9.Google Scholar
  76. 76.
    Wu S, Ni Y, Li H, Pan L, Yang D, Baccarelli AA, Deng F, Chen Y, Shima M, Guo X. Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China. Environ Int. 2016;94:76–82.CrossRefPubMedGoogle Scholar
  77. 77.
    Xiao S, Liu R, Wei Y, Feng L, Lv X, Tang F. Air pollution and blood lipid markers levels: estimating short and long-term effects on elderly hypertension inpatients complicated with or without type 2 diabetes. Environ Pollut. 2016;215:135–40.CrossRefPubMedGoogle Scholar
  78. 78.
    Xu X, Yavar Z, Verdin M, Ying Z, Mihai G, Kampfrath T, Wang A, Zhong M, Lippmann M, Chen LC, Rajagopalan S, Sun Q. Effect of Early Particulate Air Pollution Exposure on Obesity in Mice: Role of p47phox. Arterioscler Thromb Vasc Biol. 2010;30(12):2518-2527.Google Scholar
  79. 79.
    Xu Q, Li X, Wang S, Wang C, Huang F, Gao Q, Wu L, Tao L, Guo J, Wang W, Guo X. Fine particulate air pollution and hospital emergency room visits for respiratory disease in urban areas in Beijing, China, in 2013. PLoS One. 2016;11(4):e0153099.CrossRefPubMedPubMedCentralGoogle Scholar
  80. 80.
    Xu Q, Wang S, Guo Y, Wang C, Huang F, Li X, Gao Q, Wu L, Tao L, Guo J, Wang W, Guo X. Acute exposure to fine particulate matter and cardiovascular hospital emergency room visits in Beijing, China. Environ Pollut. 2017;220(Pt A):317–27.CrossRefPubMedGoogle Scholar
  81. 81.
    Ye Q, Fu JF, Mao JH, Shen HQ, Chen XJ, Shao WX, Shang SQ, Wu YF. Haze is an important medium for the spread of rotavirus. Environ Pollut. 2016;216:324–31.CrossRefPubMedGoogle Scholar
  82. 82.
    Yin P, Wang H, Vos T, Li Y, Liu S, Liu Y, Liu J, Wang L, Naghavi M, Murray CJ, Zhou M. A Subnational Analysis of Mortality and Prevalence of COPD in China From 1990 to 2013: Findings From the Global Burden of Disease Study 2013. Chest. 2016;150(6):1269-1280.Google Scholar
  83. 83.
    ZauliSajani S, Scotto F, Lauriola P, Galassi F, Montanari A. Urban air pollution monitoring and correlation properties between fixed-site stations. J Air Waste Manag Assoc. 2004;54:1236–41.CrossRefGoogle Scholar
  84. 84.
    Zeng Q, Ni Y, Jiang G, Li G, Pan X. The short term burden of ambient particulate matters on non-accidental mortality and years of life lost: a ten-year multi-district study in Tianjin, China. Environ Pollut. 2017;220(Pt A):713–9.CrossRefPubMedGoogle Scholar
  85. 85.
    Zhang P, Dong G, Sun B, Zhang L, Chen X, Ma N, Yu F, Guo H, Huang H, Lee YL, Tang N, Chen J. Long-term exposure to ambient air pollution and mortality due to cardiovascular disease and cerebrovascular disease in shenyang. China PLoS ONE. 2011;6(6):e20827.CrossRefPubMedGoogle Scholar
  86. 86.
    Zhang J, Mauzerall DL, Zhu T, Liang S, Ezzati M, Remais JV. Environmental health in China: progress towards clean air and safe water. Lancet. 2010;375:1110–9.CrossRefPubMedGoogle Scholar
  87. 87.
    Zhang Z, Wang J, Guo M, Xiong M, Zhou Q, Li D, Shu J, Lu W, Sun D. Air quality improvement during 2010 Asian games on blood coagulability in COPD patients. Environ SciPollut Res Int. 2016;23(7):6631–8.CrossRefGoogle Scholar
  88. 88.
    Zhao X, Sun Z, Ruan Y, Yan J, Mukherjee B, Yang F, Duan F, Sun L, Liang R, Lian H, Zhang S, Fang Q, Gu D, Brook JR, Sun Q, Brook RD, Rajagopalan S, Fan Z. Personal black carbon exposure influences ambulatory blood pressure: air pollution and cardiometabolic disease (AIRCMD-China) study. Hypertension. 2014;63(4):871–7.CrossRefPubMedPubMedCentralGoogle Scholar
  89. 89.
    Zhao Y, Qian ZM, Wang J, Vaughn MG, Liu YQ, Ren WH, Dong GH. Does obesity amplify the association between ambient air pollution and increased blood pressure and hypertension in adults? Findings from the 33 communities Chinese health study. Int J Cardiol. 2013;168(5):e148–50.CrossRefPubMedGoogle Scholar
  90. 90.
    Zhao A, Chen R, Wang C, Zhao Z, Yang C, Lu J, Chen X, Kan H. Associations between size-fractionated particulate air pollution and blood pressure in a panel of type II diabetes mellitus patients. Environ Int. 2015;80:19–25.Google Scholar
  91. 91.
    Zhou M, Wang H, Zhu J, Chen W, Wang L, Liu S, Li Y, Wang L, Liu Y, Yin P, Liu J, Yu S, Tan F, Barber RM, Coates MM, Dicker D, Fraser M, González-Medina D, Hamavid H, Hao Y, Hu G, Jiang G, Kan H, Lopez AD, Phillips MR, She J, Vos T, Wan X, Xu G, Yan LL, Yu C, Zhao Y, Zheng Y, Zou X, Naghavi M, Wang Y, Murray CJ, Yang G, Liang X. Cause-specific mortality for 240 causes in China during 1990-2013: a systematic subnational analysis for the Global Burden of Disease Study 2013. Lancet. 2016;387(10015):251-72.Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  • Li-Wen Hu
    • 1
  • Wayne R. Lawrence
    • 2
  • Yimin Liu
    • 3
  • Bo-Yi Yang
    • 1
  • Xiao-Wen Zeng
    • 1
  • Wen Chen
    • 1
  • Guang-Hui Dong
    • 1
  1. 1.Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Department of Preventive Medicine, School of Public HealthSun Yat-sen UniversityGuangzhouChina
  2. 2.Department of Epidemiology and Biostatistics, School of Public HealthState University of New YorkAlbanyUSA
  3. 3.Laboratory of Occupational Environment and Health Effects, Guangzhou Key Medical Discipline of Occupational Health Guardianship, Guangzhou Prevention and Treatment Center for Occupational DiseasesGuangzhou Twelfth People’s HospitalGuangzhouChina

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