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Paravalvular Leakage After Transcatheter Aortic Valve Implantation

  • Zouhair Rahhab
  • Nicolas M. Van MieghemEmail author
Chapter
  • 359 Downloads

Abstract

Transcatheter aortic valve implantation (TAVI) is the treatment of choice for inoperable or high-risk patients with severe aortic stenosis and is now expanding to intermediate- and low-risk patients [1–3]. A frequently seen complication after TAVI is paravalvular leakage (PVL), which is considered the Achilles’ heel of TAVI since several studies have shown an association with worse outcome [4–6]. Several trials and registries reported PVL rates ranging from 40% to 67% for trivial-mild leaks and from 7% to 20% for moderate-severe leaks [1, 7]. The wide variability of these frequencies may be partly related to the transcatheter heart valve (THV) design but may also reflect different methodologies for PVL assessment. Accurate PVL quantification remains challenging since there is no standardized method yet.

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© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  1. 1.Department of CardiologyThoraxcenter, Erasmus Medical CenterRotterdamThe Netherlands
  2. 2.Department of Interventional CardiologyThoraxcenter, ErasmusMCRotterdamThe Netherlands

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