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The Role of Simulation for Preoperative Planning in Patients Requiring Mechanical Circulatory Support

  • Massimo CapocciaEmail author
  • Sanjeet Avtaar Singh
  • Claudio De Lazzari
Conference paper
Part of the IFMBE Proceedings book series (IFMBE, volume 65)

Abstract

Mathematical modelling and simulation have the potential to become clinically applicable tools for detailed evaluation of the cardiovascular system and clinical decision-making to guide therapeutic intervention. This approach has a great potential for application in heart failure where the impact of left ventricular assist devices (LVADs) has played a significant role as a bridge to transplant and more recently as a long-term solution for non eligible candidates. We sought to investigate the value of simulation in the context of a heart failure patient with a view to predict or guide further management. CARDIOSIM© software was used to find out the most appropriate course of action to apply in this clinical setting. The outcome of the simulation was compared with the decision previously made in the clinical environment. Although there was an encouraging agreement, other factors play a role in the clinical decision process. Patient-specific modelling may add a more quantitative approach but requires willingness to accept a different way of thinking.

Keywords

Ventricular assist device Heart failure Simulation CARDIOSIM© Modelling 

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References

  1. 1. Doshi D, Burkhoff D (2016) Cardiovascular Simulation of Heart Failure. Pathophysiology and Therapeutics. J Card Fail 22(4):303–311.Google Scholar
  2. 2. De Lazzari C, Genuini I, Pisanelli DM, D’Ambrosi A, Fedele F (2014) Interactive simulator for e-Learning environments: a teaching software for health care professionals. BioMedical Engineering OnLine 13:172.Google Scholar
  3. 3. Suga H, Sagawa K, Shoukas AA (1973) Load Independence of the Instantaneous Pressure-Volume Ratio of the Canine Left Ventricle and Effects of Epinephrine and Heart Rate on the Ratio. Circ Res 32:314–322.Google Scholar
  4. 4. Vandenberghe S, Segers P, Steendijk P, Meyns B, Dion RAE, Antaki JF, Verdonck P (2006) Modelling Ventricular Function during Cardiac Assist: Does Time-Varying Elastance Work? ASAIO J 52:4–8.Google Scholar
  5. 5. Korakianitis T, Shi Y (2006) A concentrated parameter model for the human cardiovascular system including heart valve dynamics and atrioventricular interaction. Med Eng & Phys 28:613–628.Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Massimo Capoccia
    • 1
    • 2
    Email author
  • Sanjeet Avtaar Singh
    • 3
  • Claudio De Lazzari
    • 4
    • 5
  1. 1.Department of Cardiac SurgeryUniversity Hospitals of Leicester NHS TrustLeicesterUK
  2. 2.Department of Biomedical EngineeringUniversity of StrathclydeGlasgowUK
  3. 3.Golden Jubilee National HospitalClydebank, GlasgowUK
  4. 4.National Research CouncilInstitute of Clinical Physiology UOS of RomeRomeItaly
  5. 5.National Institute for Cardiovascular Research (I.N.R.C.)BolognaItaly

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