Nonsteroidal Anti-inflammatory Drug-Induced Enteropathy and Other Inflammatory Lesions of the Small Bowel

  • Seong Ran Jeon


Inflammatory lesions of the small bowel, other than those found in inflammatory bowel disease (IBD), are diverse and can result from a variety of insults including nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy, infectious disease such as tuberculous or cytomegalovirus enteritis, ischemia, and others. Although capsule endoscopy (CE) and device-assisted enteroscopy (DAE) are available, the differential diagnosis of small bowel disease can be difficult. CE findings of NSAID-induced enteropathy range from erosions or ulcers to severe lesions such as diaphragms. Tuberculous enteritis may occur frequently on the antimesenteric side of the intestine, which can result in a patulous ileocecal valve, transverse ulcers, pseudopolyps, strictures, and cicatricial changes. Endoscopic findings of edematous mucosal lesions with a loss of vascular vessels or a dusky pattern with scattered discrete ulcerations and strictures may be observed in patients with ischemia. Portal hypertensive enteropathy can be classified into mucosal inflammatory-like abnormalities and vascular lesions. This chapter summarizes the experience with CE and DAE for various inflammatory lesions except IBD of the small bowel.


NSAID-induced enteropathy Tuberculous enteritis Ischemic enteritis Portal hypertensive enteropathy 



Sung Noh Hong, Department of Medicine, Sungkyunkwan University School of Medicine, Seoul; Hong Jun Park, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju; Hyun Joo Song, Department of Internal Medicine, Jeju National University School of Medicine, Jeju, South Korea.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Seong Ran Jeon
    • 1
  1. 1.Department of Internal MedicineSoonchunhyang University College of MedicineSeoulSouth Korea

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