Prelabor Rupture of Membranes

  • Parneet Kaur
  • Surbhi Saini


Spontaneous rupture of membranes is a normal component of labor and delivery. Premature rupture of the membranes is defined as rupture of membranes before the onset of labor, and if it occurs before 37 weeks, it is termed preterm prelabor rupture of membranes (PPROM). If such an event occurs near or beyond term, it raises less concern about the health of the mother and neonate. PPROM, on the other hand, is more challenging due to increased risk of prematurity to the fetus and chorioamnionitis in the mother. Expectant management and immediate delivery are potential options in these patients. In women with PROM at term, labor should be induced immediately, generally with oxytocin. When PROM occurs before 34 weeks of gestation, expectant management is generally advocated, provided there are no maternal or fetal contraindications. They should be given a course of antibiotics (latency antibiotics), corticosteroids for fetal lung maturity, intrapartum group B streptococcal prophylaxis, and magnesium sulfate for neuroprotection if delivery is imminent before 32 weeks. Any evidence of intrauterine infection should be an indication for abandoning the expectant management. When PPROM occurs between 34 and 37 weeks of gestation, the obstetrician faces a clinical dilemma, and different management options are followed according to institutional protocols.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  • Parneet Kaur
    • 1
  • Surbhi Saini
    • 1
  1. 1.Department of Obstetrics & GynaecologyGovernment Medical CollegePatialaIndia

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