A Study of Alzheimer’s Disease Based on DTI Gaussian Mixture Analysis
Early clinical diagnosis of Alzheimer’s disease (AD) is beneficial for medications that delay its progression. However, current diagnosis of AD is still based on the observation of clinical symptoms from the family members and the MMSE score test from the doctors. Since diffusional tensor imaging (DTI) has long been used to detect microstructural changes in cerebral white matter (WM), we conducted a multi-parameter comparison on structures of WM using DTI, aiming to access the relation between neuroanatomical variations and AD onset.
Research supported by the Key Cultivating Project of Harbin Institute of Technology, and High-end Talent Oversea Returnees Foundation of Shenzhen (KQC201109020052A).