Structural, Contractile and Electrophysiological Adaptations of Cardiomyocytes to Chronic Exercise

  • A. Krzesiak
  • N. Delpech
  • S. Sebille
  • C. Cognard
  • A. Chatelier
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 999)


Cardiac beneficial effects of chronic exercise is well admitted. These effects mainly studied at the organ and organism integrated levels find their origin in cardiomyocyte adaptation. This chapter try to highlight the main trends of the data related to the different parameters subject to such adaptations. This is addressed through cardiomyocytes size and structure, calcium and contractile properties, and finally electrophysiological alterations induced by training as they transpire from the literature. Despite the clarifications needed to decipher healthy cardiomyocyte remodeling, this overview clearly show that cardiac cell plasticity ensure the cardiac adaptation to exercise training and offers an interesting mean of action to counteract physiological disturbances induced by cardiac pathologies.


Structure Contractile Electrophysiological adaptation Cardiomyocytes Exercise 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  • A. Krzesiak
    • 1
    • 2
  • N. Delpech
    • 2
  • S. Sebille
    • 1
  • C. Cognard
    • 1
  • A. Chatelier
    • 1
  1. 1.Equipe Transferts Ioniques et Rythmicité Cardiaque (TIRC), Lab. Signalisation et Transports Ioniques Membranaires (STIM)ERL CNRS/Université de Poitiers n°7368, Faculté des Sciences Fondamentales et AppliquéesPoitiers Cedex 9France
  2. 2.Laboratoire Mobilité, Vieillissement & Exercice (MOVE) - EA 6314Faculté des Sciences du Sport Bât C6, 8, allée Jean MonnetPoitiers Cedex 9France

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