Stem Cell Based Biotherapy for Radiation Related Injury

Chapter

Abstract

Radiation injury occurs after nuclear explosives, radiological or nuclear terrorism, nuclear accidents, and radiation therapy in combination with surgery, and it is more complicated and difficult to heal than single radiation or wound injuries. The stem cell-based therapy holds promise for radiation related injuries treatment. In this review, we summarized some representative biological properties of MSCs pre- and post-irradiation, discussed the feasibility of MSCs to apply to the treatment of radiation injuries on animal models and clinical patients, and elucidated the mechanisms of MSCs-based therapy to radiation injuries.

Keywords

Radiation Stem cells Skin Radiation related injuries Biotherapy 

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Copyright information

© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  1. 1.State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, Institute of Combined Injury, College of Preventive MedicineThird Military Medical UniversityChongqingChina

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