Pregnancy After Cardiac Valve Replacement
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Pregnancy after heart valve replacement is highly risky for both the mother and child due to the aggravation of maternal heart function and the adverse effects of some drugs, such as anticoagulant or antiarrhythmic drugs.
The recent decrease in the prevalence of rheumatic heart disease among young women has also decreased the use of mechanical heart valves. Developments in cardiac surgery have replaced mechanical heart valves with bioprosthetic heart valves. However, advances in cardiac surgery have even enabled women with mechanical heart valves to survive for a long term. For such women, long-term management of coagulability is absolutely necessary. The management of pregnancy after mechanical valve replacement is most difficult due to this need for anticoagulant therapy.
KeywordsPregnancy after cardiac valve replacement Mechanical valve Bioprosthetic valve Ross procedure
- 2.American College of Obstetricians and Gynecologists: Cardiac diseases in pregnancy. Technical Bulletin No 168, 1992Google Scholar
- 12.Bates SM, Greer IA, Middeldorp S, Veenstra DL, Prabulos AM, Vandvik PO, American College of Chest Physicians (2012) VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141(2 Suppl):e691S–e736S. https://doi.org/10.1378/chest.11-2300CrossRefPubMedPubMedCentralGoogle Scholar
- 17.Uetsuka Y, Hosoda S, Kasanuki H, Aosaki M, Murasaki K, Ooki K et al (2000) Optimal therapeutic range for oral anticoagulants in Japanese patients with prosthetic heart valves: a preliminary report from a single institution using conversion from thrombotest to PT-INR. Heart Vessel 15:124–128CrossRefGoogle Scholar
- 18.Yamaguchi T (2000) Optimal intensity of warfarin therapy for secondary prevention of stroke in patients with nonvalvular atrial fibrillation: a multicenter, prospective, randomized trial: Japanese Nonvalvular Atrial Fibrillation-Embolism Secondary Prevention Cooperative Study Group. Stroke 31:817–821CrossRefGoogle Scholar