Telocytes pp 397-402 | Cite as

Juxtacerebral Tissue Regeneration Potential: Telocytes Contribution

  • Laura Cristina Ceafalan
  • Bogdan Ovidiu Popescu
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 913)


It is well proved already that neurogenesis does take place in mammals’ brain, including human brain. However, neurogenesis by itself is not able to compensate for brain tissue loss in serious neurological diseases, such as stroke, brain trauma or neurodegenerative disorders. Recent evidences show that neural stem cell niches are present not only in classical locations, such as subventricularor subgranular zones, but in other areas as well, including tissues contiguous to the brain (meninges and choroid plexus).In this chapter we revise the relationship of neural stem cells with interstitial cells (mainly telocytes), which we think is significant, and we describe what is known about the juxtacerebral tissue neurogenesis potential.


Traumatic Brain Injury Amyotrophic Lateral Sclerosis Neural Stem Cell Choroid Plexus Adult Neurogenesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We do thank Dr. Mihaela Gherghiceanu for providing us the EM figures and for the fruitful discussions and advice.


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Copyright information

© Springer Science+Business Media Singapore 2016

Authors and Affiliations

  • Laura Cristina Ceafalan
    • 1
    • 2
  • Bogdan Ovidiu Popescu
    • 3
    • 2
  1. 1.Department of Cellular and Molecular Biology and Histology‘Carol Davila’ University of Medicine and PharmacyBucharestRomania
  2. 2.Department of Molecular Medicine and Neuroscience‘Victor Babeș’ National Institute of PathologyBucharestRomania
  3. 3.Department of Neurology, Colentina Clinical Hospital‘Carol Davila’ University of Medicine and PharmacyBucharestRomania

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