Drug Modification

  • Hamid Reza Rezaie
  • Mohammadhossein Esnaashary
  • Abolfazl Aref arjmand
  • Andreas Öchsner
Part of the SpringerBriefs in Applied Sciences and Technology book series (BRIEFSAPPLSCIENCES)


Physical, chemical, and biological properties of a drug carrier determine how it can obtain to its predetermined aim. In this chapter, some of these features are evaluated.


  1. 1.
    Veiseh O, Gunn JW, Zhang M (2010) Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging. Adv Drug Deliv Rev 62:284–304. Scholar
  2. 2.
    Parodi A, Corbo C, Cevenini A, Molinaro R, Palomba R, Pandolfi L, Agostini M, Salvatore F, Tasciotti E (2015) Enabling cytoplasmic delivery and organelle targeting by surface modification of nanocarriers. Nanomedicine 10:1923–1940. Scholar
  3. 3.
    Yu W, Zhang N (2009) Surface modification of nanocarriers for cancer therapy. Curr Nanosci 5:123–134. Scholar
  4. 4.
    Y X, Y D (2009) Recent advances in biological strategies for targeted drug delivery. Cardiovasc Hematol Disord-Drug Targets 9:206–221.
  5. 5.
    Mornet S, Vasseur S, Grasset F, Duguet E (2004) Magnetic nanoparticle design for medical diagnosis and therapy. J Mater Chem 14:2161. Scholar
  6. 6.
    Sen Gupta A (2016) Role of particle size, shape, and stiffness in design of intravascular drug delivery systems: insights from computations, experiments, and nature. Wiley Interdiscip Rev Nanomedicine Nanobiotechnology 8:255–270. Scholar
  7. 7.
    Anselmo AC, Mitragotri S (2017) Impact of particle elasticity on particle-based drug delivery systems. Adv Drug Deliv Rev 108:51–67. Scholar

Copyright information

© The Author(s) 2018

Authors and Affiliations

  • Hamid Reza Rezaie
    • 1
  • Mohammadhossein Esnaashary
    • 1
  • Abolfazl Aref arjmand
    • 1
  • Andreas Öchsner
    • 2
  1. 1.Department of Engineering Materials, Ceramic and Biomaterial DivisionIran University of Science and TechnologyTehranIran
  2. 2.Faculty of Mechanical EngineeringEsslingen University of Applied SciencesEsslingenGermany

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