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Engineering Virus-Induced African Cassava Mosaic Virus Resistance by Mimicking a Hypersensitive Reaction in Transgenic Cassava

  • Peng ZhangEmail author
  • Johannes Fütterer
  • Petra Frey
  • Ingo Potrykus
  • Johanna Puonti-Kaerlas
  • Wilhelm Gruissem

Abstract

African cassava mosaic disease (ACMD) is caused by African cassava mosaic virus (ACMV), a whitefly-transmitted geminivirus with bipartite genome denoted DNA-A and -B. It has been rated one of the most important diseases of cassava in Africa. Due to high heterozygosity and the low fertility of many local varieties, it is difficult to produce ACMV resistant varieties by traditional breeding such as the inter- and intra-specific crosses. Biotechnology provides an alternative approach to complementing the efforts in traditional breeding. Current progress in cassava genetic transformation makes it possible to produce ACMV-resistant cassava from different virus resistance approaches.

Keywords

Manihot esculenta genetic transformation ACMV resistance barnase and barstar virus induced cell death 

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References

  1. Hong Y, Saunders K, Hartley M and Stanley J (1996) Resistance to geminivirus infection by virus-induced expression of dianthin in transgenic plants. Virology 220: 119–127.PubMedCrossRefGoogle Scholar
  2. Frey PM, Scharer-Hernandez N, Futterer J, Potrykus I, Puonti-Kaerlas J (2001) Simultaneous analysis of the bidirectional African cassava mosaic virus promoter activity using two different luciferase genes. Virus Genes 22: 231–242.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2003

Authors and Affiliations

  • Peng Zhang
    • 1
    Email author
  • Johannes Fütterer
    • 1
  • Petra Frey
    • 1
  • Ingo Potrykus
    • 1
  • Johanna Puonti-Kaerlas
    • 2
  • Wilhelm Gruissem
    • 1
  1. 1.Institute of Plant SciencesZürichSwitzerland
  2. 2.European Patent OfficeMunichGermany

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