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A Centrifugal Microfluidic Platform — A Comparison

  • Marc J. Madou
  • Yumin Lu
  • Siyi Lai
  • Jim Lee
  • Sylvia Daunert
Conference paper

Abstract

The fluidic platform introduced here is a multi-purpose micro analytical laboratory on a compact disc (CD) 1,2. This system is based on the centrifugal force, in which fluidic flow can be controlled by the spinning rate of the CD and thus a whole range of fluidic functions including valving, mixing, metering, splitting, and separation can be implemented. Furthermore, optical detection such as absorption and fluorescence can be incorporated into the CD control unit to obtain signals from pre-specified positions on the disc. In this paper we present data on a two-point calibration system built on the CD platform and we compared this microfluidic platform with alternative fluidic systems.

Keywords

microfluidics centrifuge photolithography SU-8 

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Reference

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    D.C. Duffy, H.L. Gills, J. Lin, N.F. Sheppard, G.J. Kellogg, Anal. Chem. 71 (1999), 4669.CrossRefGoogle Scholar
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    M.J. Madou, G.J. Kellogg, The LabCDTM: A centrifuge-based microfluidic platform for diagnostics. in SPIE. 1998, San Jose, CA.Google Scholar
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    E. Jacobs, E. Vadasdi, L. Sarkozi, N. Coman, Clin. Chem. 39 (1993), 1069.Google Scholar
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    J.V. Valentino, J. Goldenberg. Introduction’ to computer numerical control Prentice Hall, 1993Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2000

Authors and Affiliations

  • Marc J. Madou
    • 1
  • Yumin Lu
    • 1
  • Siyi Lai
    • 2
  • Jim Lee
    • 2
  • Sylvia Daunert
    • 3
  1. 1.Department of Materials Science and EngineeringThe Ohio State UniversityUSA
  2. 2.Department of Chemical EngineeringThe Ohio State UniversityUSA
  3. 3.Department of ChemistryUniversity of KentuckyUSA

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