The Suppressive Effect of Electrolyzed Reduced Water on Lipid Peroxidation
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We examined the suppressive effect on lipid peroxidation of electrolyzed reduced water (ERW), which exhibited reactive oxygen species (ROS)-scavenging activity in vitro and in cultured cells. The oxidation of linoleic acid by 2, 2’-azobis (2-amidinopropane) hydrochloride (AAPH) was suppressed by ERW in vitro. ERW also suppressed the lipid peroxidation in cell membrane of mouse lymphoblast YAC-1 cells. Transparent electron microscopic analysis revealed that platinum in ERW existed as a colloidal form of nm size. Concentrated ERW suppressed the lipid peroxidation in a manner dependent upon the concentration of platinum nanocolloids, and chemical synthesized platinum nanocolloids exhibited a similar suppressive effect on lipid peroxidation to that of ERW, suggesting that platinum nanocolloids contained in ERW were reducing agents to suppress the lipid peroxidation.
KeywordsLipid Peroxidation Linoleic Acid Suppressive Effect Hypochloric Acid Colloidal Form
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