Hypertension appeared to result directly from bilateral nephrectomy in early studies, suggesting that nephrectomy terminated normal secretion of a depressor substance or normal metabolism of a pressor substance. But these protocols were often complicated by progressing uremia and lack of precise control of body fluids. More recently, chronic hemodialysis of anephric patients has shown that renoprival hypertension will not occur when precautions are taken to prevent overhydration. Blood pressure control in anephrics is linked to exchangeable sodium and extracellular fluid volume.
KeywordsCardiac Output Blood Pressure Control Sodium Excretion Renal Medulla Physiological Importance
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