Thalidomide and Congenital Abnormalities

  • W. G. McBride


Sir,—Congenital abnormalities are present in approximately 1.5% of babies. In recent months I have observed that the incidence of multiple severe abnormalities in babies delivered of women who were given the drug thalidomide (‘Distaval’) during pregnancy, as an anti-emetic or as a sedative, to be almost 20%.


Public Health Congenital Abnormality Case History Early Pregnancy Federal Republic 
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© The Lancet Ltd 1961

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  • W. G. McBride

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