Molecular Calculations and Thermodynamical Considerations on the Solubility Enhancement of Triflumizole by Cyclodextrin Complexation

  • G. Köhler
  • H. Viernstein
  • P. Wolschann
Conference paper


Complexation of pesticides (fungicides, herbicides, insecticides, etc.) with cyclodextrins results in advantageous modifications of their properties like e.g. enhanced solubility and therefore a better activity combined with a reduced application concentration. The activity of the fungicide Triflumizole encapsulated in β-cyclodextrin was investigated and thermodynamical parameters of the association process were determined.


Inclusion Complex Association Complex Solubility Enhancement Cyclodextrin Complex Advantageous Modification 
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Copyright information

© Springer Science+Business Media Dordrecht 1996

Authors and Affiliations

  • G. Köhler
    • 1
  • H. Viernstein
    • 1
  • P. Wolschann
    • 1
  1. 1.Institut für Pharmazeutische Technologie und Institut für Theoretische Chemie und Strahlenchemie derUniversität WienWienÖsterreich

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