Interferon Alfa Induce Tnf Elevations in vivo. Correlation with Other Acute Phase Reactants.

  • Morton A. Scheinberg
  • Eliana Chapira
  • Marcia Gordon de Carvalho
  • Maria Isabel Mota
  • Merrill D. Benson
Chapter

Abstract

Patients with solid Neoplasms requiring therapy with inter feron had serial measurements of IL-1, TNF, and SAA Evalua ted before and after repeated injections. TNF elevations were observed in all patients while IL-1 and SAA showed no significant changes.

Keywords

Tumor Necrosis Factor Acute Phase Reactant Repeated Injection Constitutional Symptom Tumor Necrosis Factor Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. 1.
    Fighen, R.A.: ‘Biotherapy in clinical practice’ (1989) Seminars in Hematology 26: 15–24, 1989.Google Scholar
  2. 2.
    Parkinson, DR.: ‘Cytokines in Cancer Therapy’ (1989) Urology 34: 87–96.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1991

Authors and Affiliations

  • Morton A. Scheinberg
    • 1
    • 2
  • Eliana Chapira
    • 1
    • 2
  • Marcia Gordon de Carvalho
    • 1
    • 2
  • Maria Isabel Mota
    • 1
    • 2
  • Merrill D. Benson
    • 1
    • 2
  1. 1.Department of Rheumatology/ImmunologyCancer Institute Arnaldo Vieira de CarvalhoSão PauloBrazil
  2. 2.Rheumatology Section Richard Roudebush Veterans Administration Medical CenterIndiana University School of MedicineUSA

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