The Carnitine System pp 7-20 | Cite as
Carnitine-dependent pathways in heart muscle
Dedicated to the memory of E. Jack Davis (1930–1993)
Chapter
Abstract
Heart and skeletal muscle normally cover most of their energy needs by oxidizing fatty acids. When rat heart is offered both glucose and high concentrations of fatty acids, fatty acids are the preferred substrate even in the presence of insulin. Under such conditions 90% of the CO2 produced will derive from fatty acids [1, 2].
Keywords
Fatty Acid Oxidation Erucic Acid Citric Acid Cycle Heart Mitochondrion Carnitine Palmitoyltransferase
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