Effect of tumour growth on inflammatory macrophages
Studies in many laboratories have led to the speculation that macrophages probably play a significant role in host defence against neoplasia. It has been shown both in vitro and in vivo that macrophages can destroy tumour cells via different pathways, specific1 or otherwise2. On the other hand it has been demonstrated that patients with neoplasms have a depressed monocyte chemotactic responsiveness3 and that macrophage accumulation in response to inflammatory stimuli is impaired during growth of experimental tumours4,5.
KeywordsAlveolar Macrophage Mycobacterium Bovis Macrophage Accumulation Macrophage Response Inflammatory Macrophage
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