Inflammation: Mechanisms and Treatment pp 573-573 | Cite as
Modification of antibody responses during non-specific acute inflammation (Abstract)
Chapter
Abstract
It has been previously shown that non-specific acute inflammatory reactions are able to modify the activity of lymphocytes and macrophages. In the present work we investigated whether such a reaction could interfere with the development of antibody responses. For this purpose, (C57B1/6xDBA/2)F1 mice were immunized with sheep red blood cells (SRBC) as a thymus dependent antigen or with TNP-LPS as a thymus-independent one, from 1 h to 5 days after the intrapleural injection of calcium pyrophosphate (CaPP) microcrystals or a dextran solution (MW 40 000).
Keywords
Fold Increase Inflammatory Process Antibody Response Inflammatory Stimulus Press Limited
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