The use of thymopoietin as an anti-inflammatory agent (Abstract)
Following the use of levamisole as an anti-rheumatic drug and its postulated action via T suppressor cells, a study has been undertaken using thymopoietin. The preparation of thymopoietin used has been a synthetic pentapeptide. This has been found to have a significant effect on acute carrageenin pleurisy in that it caused a significant reduction in cell migration but had no effect on exudate volume. Thymopoietin also caused a reduction of the cotton pellet granuloma model. Preliminary results of a clinical trial in man show promising results.