The Mechanism of Action of Pentagastrin on Circular Muscle from Canine Gastric Corpus

  • S. M. Collins


Gut peptides and neurotransmitters induce contraction of gastrointestinal smooth muscle by interacting with specific receptors. Occupation of these receptors produces an increase in the concentration of cellular calcium, resulting in contraction of the smooth muscle cell (1). However, in most instances the mechanisms underlying peptide-induced contraction of gastrointestinal smooth muscle are poorly understood.


Smooth Muscle Cell Circular Muscle Gastrointestinal Motility Extracellular Calcium Muscle Strip 
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© MTP Press Limited 1984

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  • S. M. Collins

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