Interstitial Cells of Cajal: Selective Uptake of Methylene Blue Inhibits Slow Wave Activity
The cellular origin of intestinal slow waves is uncertain. It has been argued (2) that slow waves of small intestine originate in the longitudinal muscle layer, since the recordable activity follows this layer only, upon separation of the muscle layers. Slow-wave amplitudes, measured at various depths within the intact muscularis, reach a maximum at or near the boundary between the longitudinal and circular muscle layers (3, 5).
KeywordsMethylene Blue Muscle Layer Gastrointestinal Motility Slow Wave Activity Circular Muscle Layer
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- 5.Taylor, G.S., Daniel, E. E. and Tomita, T. (1976). Origin and mechanism of intestinal slow waves. In: Vantrappen, G. (ed). Proc. 5th int. symp. gastrointest. motil. pp. 31–36. ( Herentals: Typoff )Google Scholar