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The Ileal Brake: a Potent Mechanism for Feedback Control of Gastric Emptying and Small Bowel Transit

  • N. W. Read
  • A. McFarlane
  • R. I. Kinsman
  • S. R. Bloom

Abstract

The absorption of nutrients in the small intestine depends on both the efficiency of the epithelial transport mechanisms and the length of time that nutrients remain in contact with the absorptive epithelium [1, 2]. The existence of neurohumoral mechanisms controlling either of these functions has never been established. The aim of the present study was to investigate the possible existence of a feedback mechanism, whereby the presence of nutrients in the distal small intestine might control small intestinal transit, allowing optimal time for absorption to occur.

Keywords

Transit Time Gastric Emptying Gastrointestinal Motility Breath Hydrogen Small Intestinal Transit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© MTP Press Limited 1984

Authors and Affiliations

  • N. W. Read
  • A. McFarlane
  • R. I. Kinsman
  • S. R. Bloom

There are no affiliations available

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