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Effects of Peptide YY and Porcine Pancreatic Polypeptide on Migrating Myoelectric Complexes in the Small Intestine of the Rat

  • A. Al-Saffar
  • K. Tatemoto

Abstract

Peptide YY (PYY) is a novel peptide of 36 amino acid residue with an N-terminal tyrosine (Y) and a C-terminal tyrosine (Y) amide (1). PYY and pancreatic polypeptide (PP) possess distinct structural similarities and therefore it has been proposed that they belong to the same family of peptides (1). PYY is localized in endocrine cells of the open type in the intestinal mucosa of several mammalian species (2). PYY decreases secretin-stimulated pancreatic secretion (1) and inhibits jejunal and colonic motility (2). Recently, Suzuki et al (3) have shown that PYY inhibits the interdigestive migrating contractions in the stomach.

Keywords

Gastrointestinal Motility Pancreatic Polypeptide Electrode Site Activity Front Colonic Motility 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© MTP Press Limited 1984

Authors and Affiliations

  • A. Al-Saffar
  • K. Tatemoto

There are no affiliations available

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