Reflux Characteristics in Health and Disease

  • A. H. Hölscher
  • H. F. Weiser


Via the development of a solid state pH-metry with little discomfort to patients it has become possible to quantitatively assess the gastroesophageal reflux (GER) in health and disease under almost physiological conditions. Based on initial studies of healthy subjects we have attempted to establish the borderline between physiological and pathological reflux (9).


Gastroesophageal Reflux Reflux Disease Lower Esophageal Sphincter Reflux Esophagitis Gastrointestinal Motility 
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  1. 1.
    DeMeester, T.R., Johnson, L.F., Joseph, G.J., Toscano, M.S., Hall, A.W., Skinner, D.B. (1976). Patterns of gastroesophageal reflux in health and disease. Ann. Surg., 184, 459.Google Scholar
  2. 2.
    Dent, J., Dodds, W.J., Friedman, R.H., Sekiguchi, T., Hogan, W.J., Arndorfer, R.C., Petrie, D.J. (1980). Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J. clin. Invest., 65, 256.Google Scholar
  3. 3.
    Euler, A.R., Byrne, W.J.,(1981). Twenty-four-hour esophageal intraluminal pH-probe testing. A comparative analysis. Gastroenterology, 80, 957PubMedGoogle Scholar
  4. 4.
    Savary, M. Miller, G. (1977). Der Ösophagus - Lehrbuch und endoskopischer Atlas. Gassman: Solothurn.Google Scholar
  5. 5.
    Siewert, J.R., Weiser, H.F., Jennewein, H.M., Waldeck, F. (1974). Clinical and manometric investigations of the lower esophageal sphincter and its reactivity to penta-gastrin in patients with hiatus hernia.Digestion, 10, 287.Google Scholar
  6. 6.
    Siewert, J.R., Blum, A.L., Waldeck, F. (1976). Funktionsstörungen der Speiseröhre. Springer: Berlin - Heidelberg - New York.CrossRefGoogle Scholar
  7. 7.
    Stanciu, C., Hoare, R.C., Bennett, J.R. (1977). Correlation between manometric and pH tests for gastro-esophageal reflux. Gut, 18, 536.PubMedCrossRefGoogle Scholar
  8. 8.
    Wallin, L., Madsen, T. (1979). 12-hour simultaneous registration of acid reflux and peristaltic activity in the esophagus. A study in normal subjects. Scand. J. Gastroent., 14, 561.Google Scholar
  9. 9.
    Weiser, H.F., Pace, F., Lepsien, G., Müller-Lissner, S.A., Blum, A.L., Siewert, J.R. (1982). Gastroösophagealer Reflux - was ist physiologisch? Dtsch. med. Wschr., 107, 366.CrossRefGoogle Scholar
  10. 10.
    Weiser, H.F. (1982). Reflux characteristics of healthy volunteers, examined by 24-hour-pH-recording. In: Wien-beck, M. (ed.). Motility of the Digestive Tract.(Raven Press: New York ).Google Scholar
  11. 11.
    Weiser, H.F., Hölscher, A.H., Siewert, J.R. (1983). Gastroösophagealer Reflux: Besteht eine Korrelation zwischen Refluxausmaß und Refluxfolgen? Dtsch. med. Wschr., 108, 930–935.Google Scholar

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© MTP Press Limited 1984

Authors and Affiliations

  • A. H. Hölscher
  • H. F. Weiser

There are no affiliations available

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