Chromosomal abnormalities in malignant lymphoid cell proliferations: recent advances

  • R. Berger
Chapter

Abstract

The coincidence of chromosomal breakpoints of acquired chromosomal rearrangements of cancer cells with protooncogene localizations has brought new insights on the pathogenetic mechanisms of cancerogenesis. Although the Burkitt lymphoma (BL) has been one of the first examples of human malignancy studied with molecular biology and molecular cytogenetic techniques, we now know other examples of malignant lymphoid cell proliferations illustrating this new approach of cancer study. The recognition of new chromosomal abnormalities and of new genes or DNA sequences has brought significant advances in this field since the last few years.

Keywords

Acute Lymphoblastic Leukemia Chronic Lymphocytic Leukemia Burkitt Lymphoma Hairy Cell Leukemia Recombination Signal Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© The Organising Committee of the Ninth International Chromosome Conference, Marseille 1987

Authors and Affiliations

  • R. Berger
    • 1
  1. 1.Hôpital Saint-LouisINSERM U.301ParisFrance

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