New Assays Based on Laminar Fluid Diffusion Interfaces—Results from Prototype and Product Testing

Abstract

Central to Micronics’ microfluidics technology platforms is the generation and use of Laminar Fluid Diffusion Interfaces (LFDIs). One of the embodiments of LFDIs is in diffusion-based detection technology, which is based on the parallel flow of individual streams in a single microfluidic channel. Micronics’ T-Sensor® based Chemical Analysis System (CAS) harnesses diffusion to identify unknown concentrations of chemical species, allowing researchers to perform multiple assays on a single version of a disposable microfluidic cartridge. Implementations of both a prototype portable device and a benchtop system are demonstrated, with CV’s ranging from 2.6 to 10%.