Functionalized Parylene Coatings for Microfluidic Applications
The need to increase the throughput of drug-discovery processes while reducing costs continues to drive the development of microfluidic assays. The deposition of thin polymer films that establish chemically defined interfaces offers a unique way to overcome these limitations. We report a stable and functionalized modification of PDMS microfluidic devices by chemical vapor deposition (CVD) polymerization with poly[para-xylylene] coatings. These coating further has the advantages of allowing deposition over complex three dimensional geometries and into cavities — as long as the latter allow sufficient diffusion.
KeywordsCVD reactive coating surface modification cell assay
Unable to display preview. Download preview PDF.