Passive Immunity Against Enteric Viral Infections of Piglets

  • E. H. Bohl
  • Linda J. Saif
Part of the Current Topics in Veterinary Medicine and Animal Science book series (CTVM, volume 12)


An immunologic system has evolved whereby newborn animals derive an appreciable degree of protection from enteric infections by means of passive immunity. This report explores some of the facets of this system, using infections of swine with transmissible gastroenteritis virus, rotavirus, or enterovirus as examples. In swine, and probably in most mono gastric animals, passive immunity against enteric infections is dependent on the ingestion — at normal intervals for the particular species — of colostrum or milk which contain appropriate levels of specific antibodies, with those of the IgA class being most protective. In swine, and probably in most mono gastric animals, antibodies of the IgA class appear to occur in mammary secretions only, or primarily, as a result of an appropriate antigenic stimulation of the intestinal tract. This type of information, and the variables involved, is of special value when attempting to design an immunisation programme which will provide passive immunity against enteric infections.

Many enteric infections occur as enzootics, wherein young animals become infected during the suckling period or shortly after weaning. Pigs are usually protected from rotaviral or enteroviral infections during the first 2 to 5 weeks of age because of passive immunity, after which time an intestinal infection usually occurs. The occurrence and possible significance of boosting lactogenic immunity by natural re-infection or by vaccination are discussed and some results given.


Passive Immunity Enteric Virus Enteric Infection Enteroviral Infection Mammary Secretion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© ECSC, EEC, EAEC, Brussels-Luxembourg 1981

Authors and Affiliations

  • E. H. Bohl
    • 1
  • Linda J. Saif
    • 1
  1. 1.Department of Veterinary ScienceOhio Agricultural Research and Development CenterWoosterUSA

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