The History of Crohn’s Disease

  • Harry D. Fein

Abstract

It is probable that Morgagni, as early as 1769 in De Sedibus et Causis Morborum (“The Seats and Causes of Diseases”), gave the first clinical description of a case of Crohn’s disease. In 1865, probably the first clinical and pathological description of ulcerative colitis was recorded in the annals of the Union Army Medical Corps. It was not until 1909 that Braun described several cases of inflammatory disease masses involving the small intestine. Dalziel in 1913 reported, in detail, six cases similar to those of Braun, in which tuberculosis (though suspected) was excluded by careful bacteriological studies. This evoked some acceptance that a benign, chronic, granulomatous condition of the small intestine existed which was not tuberculosis.

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Bibliography

  1. Braun H: Veber entzunollische Geschwultse, am Darm. Dtsch Z Chin 100:1, 1909.CrossRefGoogle Scholar
  2. Brooke BN, Cave DR, Gurry JF, et al: Crohn’s Disease New York, Oxford University Press, 1977.Google Scholar
  3. Crohn B, Ginzburg L, Oppenheimer GD: Regional ileitis. JAMA 99:1323, 1932.Google Scholar
  4. Dalziel TK: Chronic interstitial enteritis. Br Med J 2:1068, 1913.Google Scholar
  5. Morgagni GB: De Sedibus et Causis Morborum (The Seats and Causes of Disease) London, Millar and Cadwell, 1769. Facsimile of the 1769 edition. New York, Hafner, 1960.Google Scholar
  6. Moschowitz E, Wilensky A: Nonspecific granulomata of the intestine. Am J Med Sci 166:48, 1923.Google Scholar
  7. Moschowitz E, Wilensky A: Nonspecific granulomata of the intestine. Am J Med Sci 178:374, 1927.Google Scholar
  8. Union Army Medical Corps: Medical and Surgical History of the Rebellion, USA Washington, Circular No. 6, 1865, p 139.Google Scholar

Copyright information

© John Wright PSG Inc 1982

Authors and Affiliations

  • Harry D. Fein

There are no affiliations available

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