Bioengineering and the Skin pp 237-244 | Cite as
Relationship of intracorneal cohesion to rates of desquamation in the scaling disorders
Chapter
Summary
The relationship between intracorneal cohesion (ICC) and numbers of single corneocytes released after a scrub stimulus has been investigated in normal skin, the skin of patients with a variety of scaling disorders and in tape-stripped normal skin. A weak negative correlation has been found between ICC and the numbers of corneocytes released. The importance of this relationship in the pathophysiology of scaling is discussed.
Keywords
Atopic Dermatitis Stratum Corneum Normal Skin Weak Negative Correlation Normal Healthy Volunteer
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
- 1.King, C. S, Barton, S. P, Nicholls, S. and Marks, R. (1979). The change in properties of the stratum corneum as a function of depth.Br. J. Dermatol., 100, 165PubMedCrossRefGoogle Scholar
- 2.Nicholls, S. and Marks, R. (1977). Techniques for the estimation of intracorneal cohesion in vivo. Br. J. Dermatol. 96, 595PubMedCrossRefGoogle Scholar
- 3.Marks, R., Nicholls, S. and Fitzgeorge, D. (1977). Measurement of intracorneal cohesion in man usingin vivo techniques. J. Invest. Dermatol., 61, 299CrossRefGoogle Scholar
- 4.Guibarra, E. J. (1979). An instrument for the stimulated release of corneocytes. Bioengineering and the Skin, 1, 17Google Scholar
- 5.Roberts, D. and Marks, R. (1980). The determination of regional and age variations in the rate of desquamation: a comparison of four techniques. J. Invest. Dermatol. 74, 13PubMedCrossRefGoogle Scholar
- 6.King, C. S., Nicholls, S., Barton, S. and Marks, R. (1979). Is the stratum corneum of uninvolved psoriasic skin abnormal? Acta Dermatovener 59, 95Google Scholar
- 7.Nicholls, S. King, C. S. and Marks, R. (1978). Morphological and quantitative assessment of physical changes in the horny layer in ichthyosis. In Marks, R. and Dykes, P. J. (eds.) The Ichthyoses. (Lancaster: MTP)Google Scholar
- 8.Finlay, A. Y., Nicholls, S., King, C. S. and Marks, R. (1980). The ‘dry’ non-eczematous skin associated with atopic eczema. Br. J. Dermatol. (In press)Google Scholar
Copyright information
© MTP Press Limited 1981