Role of Messenger RNA Specific Secondary Structure in the Control of Gene Expression

  • Sylvain Blanquet
  • Guy Fayat
  • Jean-François Mayaux
  • Mathias Springer
  • Marianne Grunberg-Manago
Conference paper

Abstract

Prokaryotic messenger RNA can form specific secondary structures involved in transcription termination. These structures can be located within as well as at the end of an operon. In the case of several aminoacid biosynthetic operons, termination sites are found between the promoter and the structural part of the operon. Regulation of operon expression can be achieved by controlling transcription termination versus read-through at these termination sites. The control involves the coupling of RNA translation to the transcription process. The present review summarizes the evidence in favour of the same kind of control mechanism in the expression of E.coli phenylalanyl-tRNA synthetase operon.

Keywords

Structural Part Loop Structure Leader Peptide Transcription Termination Transcription Terminator 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© D. Reidel Publishing Company 1983

Authors and Affiliations

  • Sylvain Blanquet
    • 1
    • 2
  • Guy Fayat
    • 1
    • 2
  • Jean-François Mayaux
    • 1
    • 2
  • Mathias Springer
    • 1
    • 2
  • Marianne Grunberg-Manago
    • 1
    • 2
  1. 1.Laboratoire de BiochimieEcole PolytechniquePalaiseau CedexFrance
  2. 2.Institut de Biologie Physico-ChimiqueParisFrance

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