Radioisotope studies in cardiology pp 225-261 | Cite as
Diagnostic Utility of T1201 Imaging
Abstract
Since its introduction into medical diagnosis, Tl201 scintigraphy has provided important information concerning the non-invasive assessment of myocardial perfusion. The technique has been demonstrated to be of major importance in patients with suspected and documented coronary artery disease and provided also useful information in a variety of other cardiac disorders like cardiomyopathy, valve disease, right ventricular hypertrophy, and cardiac involvement in systemic diseases like sarcoidosis (1–19). The major clinical application of Tl201 imaging was reported in the field of coronary artery disease. In comparison to older noninvasive diagnostic tests considering ECG changes during exercise, Tl201 scintigraphy in combination with stress procedures has yielded high values of sensitivity and specificity in the detection of patients with coronary artery disease. Apart from the usual form of physical stress applying bicycle or treadmill exercise, the potential value of TI201 imaging has been considerably increased by the possibility to provoke stress conditions using high doses of intravenously given dipyridamole. This special type of stress is regarded as an important alternative in many patients unable to exercise adequately (20–28).
Keywords
Single Photon Emission Compute Tomography Left Anterior Descend Pretest Probability Multivessel Disease Coronary StenosPreview
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References
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