β-Lactam Antibiotics as Carbonyl Donors of the Active-Site Serine β-Lacta-Mases, DD-Peptidases and LL-Peptidases

  • J.-M. Ghuysen
Chapter
Part of the New Perspectives in Clinical Microbiology book series (NPCM, volume 13)

Abstract

The concept of antibacterial chemotherapy goes back to the discovery of the sulfa drugs in the 1930’s. This concept, however, was definitely established only when the first cures were achieved by penicillin in 1941. Penicillin opened the antibiotic era in which we are living now.

Keywords

Acyl Enzyme Scissile Bond Acyl Transfer Reaction Peptidoglycan Precursor Transpeptidation Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Martinus Nijhoff Publishers, Dordrecht 1987

Authors and Affiliations

  • J.-M. Ghuysen
    • 1
  1. 1.Service de Microbiology, Faculté de Médecine, Institut de Chimie, B6Université de LiègeLiège 1Belgium

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