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Long-term multicentre trial with acipimox in diabetic patients with hyperlipoproteinemia

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Atherosclerosis and Cardiovascular Diseases

Abstract

Acipimox is a new lipid-lowering agent with long-lasting antilipolytic activity chemically related to nicotinic acid (1,2). The aim o f the present trial was to study the effect of acipimox on plasma lipid levels and its tolerability during long-term treatment in diabetic patients with hyperlipoproteinemia. The trial included investigation of any influence of the drug on glucose tolerance.

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References

  1. Fuccella, L et al (1980). Inhibition of lipolysis by nicotinic acid and by acipimox. CIin. Pharmacol. Ther., 28, 790.

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  2. Stirling, C et al (1985). Effects of acipimox, a nicotinic acid derivative, on lipolysis in human adipose tissue and cholesterol synthesis in human jejunal mucosa. Clin. Sci., 68, 83.

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  3. Parsons, W B et al (1961). Studies of nicotinic acid use in hypercholesterolemia: changes in hepatic function, carbohydrate tolerance and uric acid metabolism. Arch. Int. Med., 107, 653.

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  4. Pollack, H (1962). Nicotinic acid and diabetics. Diabetes, 11, 144.

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  5. Regal, H et al (1984). Effect of a single oral dose of acipimox on glucose metabolism after intravenous glucose load in obese patients. Drugs Exptl. Clin. Res., 10, 621.

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© 1987 MTP Press Limited

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Muggeo, M., Lavezzari, M., Montoro, C., Sacchetti, G. (1987). Long-term multicentre trial with acipimox in diabetic patients with hyperlipoproteinemia. In: Lenzi, S., Descovich, G.C. (eds) Atherosclerosis and Cardiovascular Diseases. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3205-0_62

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  • DOI: https://doi.org/10.1007/978-94-009-3205-0_62

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7938-9

  • Online ISBN: 978-94-009-3205-0

  • eBook Packages: Springer Book Archive

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